Arsenal vs. Atletico Madrid Prediction, Betting Pick, Latest Champions League Odds
Arsenal, currently in the top five, will host Atletico, who sit mid-table, in a Champions League clash on Tuesday, October 21, 2025, at 19:00 UTC. The match will take place in London.
OC Staff - October 21, 2025, 8:30 AM EDT
4 Minute ReadArsenal vs Atletico: Lineups, Team News and Prediction
Arsenal, currently in the top five, will host Atletico, who sit mid-table, in a Champions League clash on Tuesday, October 21, 2025, at 19:00 UTC. The match will take place in London.
Arsenal vs Atletico Form
The Gunners head into this match on the back of a 1-0 away victory against Fulham. Arsenal have been in solid form recently, securing seven wins in their last eight matches, with their only blemish being a draw against Man City. Their defense has been particularly impressive, conceding just two goals in that period.
Atletico secured a narrow 1-0 victory against Osasuna in their last La Liga match. The visitors have been in good form themselves, winning four of their last five games, including an impressive 5-2 victory over Real Madrid. They appear to be taking more risks in attack, particularly when Alvarez is in inspired form.
Arsenal vs Atletico Head to Head
The most recent encounter between these two sides was in the 2018 Europa League semi-final, where Atletico emerged victorious.
Across the previous six meetings, Atletico have won one, Arsenal have also won one and there have been two draws.
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Arsenal vs Atletico Odds
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Arsenal vs Atletico Probable Lineups
Arsenal (4-3-3): Raya; Calafiori, Saliba, Magalhães, Timber; Rice, Zubimendi, Eze; Trossard, Gyökeres, Saka
Atletico (3-5-2): Oblak; Hancko, Giménez, L. Normand; M. Llorente, Gallagher, Barrios, Koke, G. Simeone; Alvarez, Griezmann
Arsenal vs Atletico Team News
Arsenal are dealing with several key injuries, with Jesus, Havertz, Madueke, and Ødegaard all ruled out. Trossard is expected to be full of confidence after scoring the winner against Fulham. Mikel Merino could feature in Arsenal's midfield if Arteta opts for a more physical approach, potentially benching either Eze or Trossard.
Atletico also have injury concerns, with Cardoso and Kostis sidelined, while González is doubtful. Almada, who scored the winner against Osasuna, could be included in the starting lineup. If González is unavailable, G. Simeone may start at right-wing-back.
Arsenal vs Atletico Match Facts
- Arsenal have seen under 2.5 goals in their last 3 matches against Atletico in all competitions.
Prediction: Arsenal 2-1 Atletico
Arsenal will be looking to avenge their 2018 Europa League semi-final defeat against Atletico. The Gunners have made significant progress since then and are expected to win this match.
Best Bet: Arsenal Moneyline (-170) Check out the best odds on bet365 Sportsbook
Arsenal have been very organised at the back, conceding only two goals in their last eight matches and are a good bet to win this match.
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