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Liverpool vs Real Madrid Prediction, Betting Pick, Latest Champions League Odds

Liverpool, currently positioned mid-table, will host Real Madrid, who are in the upper echelons of the Champions League table, in a highly anticipated match on Tuesday, November 4, 2025, at 20:00 at Anfield.

OC Staff - November 4, 2025, 10:10 AM EST

4 Minute Read

Liverpool vs Real Madrid: Lineups, Team News and Prediction

Liverpool, currently positioned mid-table, will host Real Madrid, who are in the upper echelons of the Champions League table, in a highly anticipated match on Tuesday, November 4, 2025, at 20:00 at Anfield.

Liverpool vs Real Madrid Form

Liverpool's Champions League campaign has been a mixed bag. They secured a convincing 2-0 victory against Aston Villa in their most recent home match in the Premier League. However, their form has been inconsistent, highlighted by a recent League Cup defeat at home to Crystal Palace (0-3).

Real Madrid arrive at Anfield in excellent form. Their last match saw them dominate Valencia with a 4-0 victory in La Liga. They boast a strong away record, although they did endure a narrow 2-1 win against Barcelona.

Liverpool vs Real Madrid Head to Head

The rivalry between Liverpool and Real Madrid is steeped in history. The most recent encounter saw Liverpool triumph 2-0 at Anfield in the Champions League last year.

However, historically, Real Madrid have dominated this fixture, winning four of the last six meetings, with one draw and one victory for Liverpool.

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Liverpool vs. Real Madrid Odds

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Liverpool vs Real Madrid Probable Lineups

Liverpool (4-2-3-1): G. Mamardashvili; A. Robertson, V. v. Dijk, I. Konaté, C. Bradley; D. Szoboszlai, C. Jones; C. Gakpo, F. Wirtz, M. Salah; H. Ekitiké

Real Madrid (4-3-3): T. Courtois; Á. Carreras, R. Asencio, É. Militão, F. Valverde; A. Güler, A. Tchouaméni, J. Bellingham; V. Júnior, K. Mbappé, B. Díaz

Liverpool vs Real Madrid Team News

Liverpool face a significant injury crisis. A. Isak, R. Gravenberch, J. Frimpong, S. Bajcetic, and A. Becker are all sidelined due to injury.

Real Madrid will be without A. Rüdiger and D. Carvajal, both nursing injuries.

Liverpool vs Real Madrid Match Facts

  • Real Madrid have won their last 3 matches in the Champions League.
  • Liverpool have won 2 of their last 3 matches in the Champions League.
  • Real Madrid have scored 8 goals and conceded 1 goal in the Champions League.

Prediction: Liverpool 2-3 Real Madrid

This promises to be a thrilling encounter between two of Europe's giants. Both teams have shown their attacking prowess this season, but Real Madrid's slightly better form and greater experience in the Champions League may give them the edge. I predict a 3-2 victory for Real Madrid, in what should be an entertaining match. Liverpool have been blending Dutch structure with a Premier League tempo. Real Madrid have been averaging the most shots on target per game of any team in the competition.

Best Bet: Over 3.5 Goals (-110) Check out the best odds on bet365 Sportsbook

Given the attacking talent on display and both teams' recent scoring records, backing over 3.5 goals in the match is a strong possibility. Real Madrid have averaged the most shots on target per game of any team this season, and Liverpool have been blending Dutch structure with a Premier League tempo.

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