Southampton vs Portsmouth Lineups, Prediction, Betting Picks & Odds

Southampton vs Portsmouth Game Preview

The South Coast derby lands at St. Mary's Stadium on Sunday, and our Southampton vs Portsmouth prediction leans firmly toward the hosts in a game built for goals.

Southampton arrive stung. A six-game unbeaten run in the Championship ended at Wrexham, where a late Keven Schlotterbeck own goal turned a road point into a defeat.

Portsmouth come in off back-to-back Championship ties with Charlton and Blackburn, and Pompey have won just one of their last five league games. That is not a resume that scares anyone.

The rivalry tilts the same way. Southampton have gone five straight without a loss to Portsmouth in all competitions, and the hosts will want to keep the bragging rights.

Southampton vs Portsmouth Recent Results

Southampton's six-game unbeaten run in the Championship ended in cruel fashion at Wrexham. The bigger picture is steady rather than spectacular, with their moneyline landing 5 times in their last 10 games against all opponents. Finn Azaz and Cyle Larin drive an attack built on counterattacks and clinical finishing, and that is where this team does its damage.

Portsmouth's moneyline would have landed just 3 times in their last 10 games against all opponents, and finishing has been their weak spot. Adrian Segecic provides the spark, getting off 3 or more shots in five of his last seven Championship outings. Pompey's long-range shooting and direct free kicks keep them dangerous even in a slump.

Southampton vs Portsmouth Lineups & Team News

Injuries & Suspensions

Southampton: M. Roerslev (Injured/out), C. Jander (Unfit)

Portsmouth: T. Waddingham (Injured/out), J. Farrell (Injured/out), M. Kosznovszky (Injured/out), F. Umeh-Chibueze (Injured/out), C. Ogilvie (Injured/out), J. Murphy (Injured/out), L. Brooke-Smith (Injured/out), T. Devlin (Injured/doubtful), K. Anderson (Unfit), C. Shaughnessy (Unfit), Marezi (Unfit)

Southampton

Caspar Jander made his long-awaited return to first-team training during the international break, though he is still listed as unfit. Cyle Larin and Daniel Peretz came back from international duty unscathed, and Tonda Eckert could make one change to the side that faced Wrexham, recalling Tom Fellows.

Portsmouth

Portsmouth will make late calls on Marko Milovanovic and Conor Shaughnessy. Keshi Anderson is back in training, but John Mousinho won't rush him back into action. The treatment room is crowded, with seven players listed as injured and T. Devlin doubtful. Both probable Southampton vs Portsmouth lineups below line up in a 4-2-3-1.

Southampton vs Portsmouth Predicted Lineup

Southampton

Formation: 4-2-3-1 (probable)

Predicted Starting Lineup: D. Peretz; J. Bree, K. Schlotterbeck, N. Wood, R. Manning; J. Ward-Prowse, F. Downes; T. Fellows, F. Azaz, L. Scienza; C. Larin

Portsmouth

Formation: 4-2-3-1 (probable)

Predicted Starting Lineup: D. Bielica; Z. Swanson, R. Poole, M. Dia, J. Meghoma; E. Adams, M. Pack; A. Kamara, A. Segecic, T. Shade; C. Bishop

Southampton vs Portsmouth Key Stats & Game Facts

• There have been 26+ shots taken in 8 of Southampton's last 8 games (Championship).
• Both teams have scored in 8 of Southampton's last 8 games (Championship).
• Leo Scienza has won 2+ fouls in 8 of his last 8 appearances (Championship).
• Cyle Larin has recorded 1+ shots on target in 7 of his last 8 appearances (Championship).
• John Swift has been carded in 2 of his last 3 appearances vs Southampton (Championship).

Southampton vs Portsmouth Prediction & Best Picks

Our Prediction

Our prediction is a Southampton win, but not a clean one. The projection hands the hosts 2.05 goals, and an attack built around Larin and Azaz has the tools to deliver. Portsmouth still find their way onto the scoreboard, with 1.18 goals projected for the visitors, because this Southampton back line is too generous to keep a shutout. That read shapes our Southampton vs Portsmouth best picks.

Best Picks

Over 2.5 goals in the Total Goals Over/Under market. The model projects a high-scoring game between Southampton and Portsmouth. Total Goals Over/Under is the market to attack here. The projected total of 3.23 goals clears the line comfortably. Southampton have also seen over 2.5 goals in each of their last 3 Championship games.

Yes in the Both Teams To Score market. Both sides are expected to find the net at St. Mary's. Both Teams To Score is the market, and the projection gives it a 60.39% probability. Southampton struggle to stop opponents creating looks and to defend set pieces, while Portsmouth bring a genuine threat from long shots and set plays.

Southampton vs Portsmouth Same Game Parlay

Our Southampton vs Portsmouth same game parlay picks stack two Cyle Larin shooting props with Both Teams To Score and Finn Azaz to score anytime.

Cyle Larin Over 1.5 in the Player Shots market. Larin has gotten off 2 or more shots in all eight of his Championship outings this season, so the volume is there every week.

Cyle Larin Over 0.5 in the Player Shots On Target market. He has put at least one shot on target in seven of his last eight Championship appearances, turning volume into accuracy.

Yes in the Both Teams To Score market. Both teams have scored in 8 of Southampton's last 8 Championship games, and Portsmouth's long-range threat gives them a path to goal.

Finn Azaz in the Anytime Goalscorer market. Azaz has fired at least two shots in 7 of his last 8 Championship outings from the central attacking role behind Larin.

At the time of writing, this Same Game Parlay pays a best price of +500 and is as short as +375 elsewhere. That's a difference in potential winnings of $13 from best to worst price.

Make sure to get the best odds on your Same Game Parlay with Oddschecker's Exclusive Same Game Parlay Comparison Tool.

Same Game Parlay odds correct at time of publishing.

Southampton vs Portsmouth Talking Points

Tonda Eckert has been cleared to stand in the dugout after an independent FA commission handed him a suspended ban following its Spygate investigation, so Southampton have their manager on the touchline for the derby. He also has a perfect home record to lean on, with Southampton winning all four of their home league games at St. Mary's this season. The Southampton vs Portsmouth betting odds back the hosts accordingly, with Southampton at -175 (Betfred) on the moneyline. The catch sits at the other end of the field. Southampton rate poorly at stopping opponents from creating looks, and Portsmouth's long-range shooting and set-piece threat can punish that.

Southampton vs Portsmouth Predictions FAQs

When does the Southampton vs Portsmouth game kick off?

The game is scheduled to kick off at 7:00 AM ET / 4:00 AM PT on Sunday, October 11, 2026.

Where is the Southampton vs Portsmouth game taking place?

The game will be played at St. Mary's Stadium in Southampton, England.

Where can I watch the Southampton vs Portsmouth game?

The game will be broadcast live on Sky Sports Main Event, Sky Sports Arena, ITV 1, and ITV Interactive.

What are the projected starting lineups for the Southampton vs Portsmouth game?

Southampton are projected to start Peretz, Manning, Schlotterbeck, Wood, Bree, Ward-Prowse, Downes, Scienza, Azaz, Fellows, and Larin. Portsmouth are expected to field Bielica, Meghoma, Poole, Dia, Swanson, Adams, Pack, Shade, Segecic, Kamara, and Bishop.

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