Roma vs Real Madrid Lineups, Prediction, Betting Picks & Latest Champions League Odds
Roma vs Real Madrid prediction, lineups, and odds for Wednesday's Champions League game. Explore top betting picks and Same Game Parlay options today.
Cody Moore - October 14, 2026, 12:22 PM EDT
7 minutesRoma vs Real Madrid Game Preview
Competition | UEFA Champions League |
|---|---|
Game Date | Wednesday, October 14, 2026 |
Game Time | 3:00 PM ET / 12:00 PM PT |
Venue (City, Stadium) | Rome, Stadio Olimpico |
José Mourinho takes Real Madrid back to the Stadio Olimpico to face his old club in the Champions League, and our Roma vs Real Madrid prediction leans firmly toward the visitors.
Roma have been tough to beat lately, but too many ties have crept in, and they are short-handed with Bryan Cristante one of three players on the injury list.
Real Madrid arrive after beating Inter in the Champions League, with Kylian Mbappé leading a 4-2-3-1 that has Vinícius Júnior and Jude Bellingham lined up behind him.
The head-to-head gives Roma little to lean on. Real Madrid have won four of the previous meetings, there have been two ties, and Roma have yet to win one.
Roma vs Real Madrid Recent Results
Roma are unbeaten in seven games in all competitions, but the wins have dried up. They opened their European account with a 1-1 tie at Fenerbahçe in the Champions League. In Serie A on Sunday, they showed real grit, holding Como to a scoreless tie after Donyell Malen was sent off. That night, it was the defense that carried them, not the attack.
Real Madrid have won four of their last five games in all competitions, and the quality of the wins stands out. They beat Serie A champions Inter in the Champions League, then got past Villarreal at the weekend even though Vinícius Júnior was sent off. Kylian Mbappé remains the focal point of a front line that keeps finding answers.
Roma vs Real Madrid Lineups & Team News
Injuries & Suspensions
Roma: B. Cristante (Injured/out), K. Koulierakis (Injured/out), M. Svilar (Injured/out)
Real Madrid: É. Militão (Injured/out), R. Asencio (Injured/out), Rodrygo (Injured/out)
Roma
The big news for the Roma vs Real Madrid lineups is that Donyell Malen is available. His red card against Como in Serie A does not carry over to the Champions League, so he is set to lead the line. Bryan Cristante, K. Koulierakis and M. Svilar are all out injured, and P. Gollini gets the probable nod in goal.
Real Madrid
Madrid get reinforcements. Eduardo Camavinga, Bernardo Silva and Arda Güler are all available after missing their last Champions League outing. Vinícius Júnior and Marc Cucurella are in line to start after being named on the bench against Villarreal. Denzel Dumfries could return at right back, and Dean Huijsen has served his suspension. Militão, Asencio and Rodrygo are out injured.
Roma vs Real Madrid Predicted Lineup
Roma
Formation: 3-4-2-1 (probable)
Predicted Starting Lineup: P. Gollini; M. Hermoso, E. Ndicka, G. Mancini; D. Rensch, M. Koné, M. d. Roon, Wesley; M. Soulé, P. Dybala; D. Malen (probable)
Real Madrid
Formation: 4-2-3-1 (probable)
Predicted Starting Lineup: T. Courtois; D. Dumfries, A. Rüdiger, D. Huijsen, M. Cucurella; A. Tchouaméni, F. Valverde; A. Güler, J. Bellingham, V. Júnior; K. Mbappé (probable)
Roma vs Real Madrid Key Stats & Game Facts
- There have been 12+ shots on target in 3 of the last 3 meetings between Real Madrid and Roma in the Champions League.
- There have been 28+ shots taken in 4 of the last 4 meetings between Real Madrid and Roma in the Champions League.
- Real Madrid have scored 2+ goals in 4 out of 4 games against Roma in the Champions League.
- Roma have had 6+ corners in 4 of their last 4 games against Real Madrid in the Champions League.
- Real Madrid have posted a shutout in 4 of their last 4 games against Roma in the Champions League.
Roma vs Real Madrid Prediction & Best Picks
Our Prediction
Our prediction is a Real Madrid win in an open game with goals at both ends. The projections give Madrid a 50.69% win probability, and the Roma vs Real Madrid betting odds tell the same story, pricing the visitors at -105 (AK Bets). Roma are stubborn, but Mbappé, Vinícius and Bellingham give Madrid too many ways to hurt a side that has been settling for ties.
Best Picks
Real Madrid to win on the Moneyline. This is our play in the Moneyline market, and the matchup history backs it. Real Madrid are undefeated in their last 7 games against Roma in all competitions. They have also scored at least twice in each of their last 6 games against Roma in all competitions.
Both Teams To Score: Yes. We are taking Yes in the Both Teams To Score market. The projection calls for 3.35 total goals, with Roma expected to contribute their share. It also puts both teams scoring at 64.5%, and with Militão and Asencio out for Madrid, Dybala, Soulé and Malen have room to work.
Roma vs Real Madrid Same Game Parlay
Our Roma vs Real Madrid same game parlay picks combine a Real Madrid moneyline win, a Kylian Mbappé goal, both teams scoring and a card for Mario Hermoso.
Real Madrid on the Moneyline: Vinícius Júnior and Marc Cucurella are in line to start and Arda Güler is available again, so Mourinho has his strongest attacking group back.
Mbappé in the Anytime Goalscorer market: he leads the line as Madrid's main goal threat, and the projection makes him a 56.22% shot to score.
Both Teams To Score: Madrid are missing Militão and Asencio, and with Dybala, Soulé and Malen all in Roma's probable XI, a home goal is very live.
Hermoso in the To Be Shown A Card market: he anchors Roma's back three against a high-intensity Madrid attack, which makes a booking a natural fit.
At the time of writing, this Same Game Parlay pays a best price of +1000 and is as short as +489 elsewhere. That's a difference in potential winnings of $51 from best to worst price.
Make sure to get the best odds on your Same Game Parlay with Oddschecker's Exclusive Same Game Parlay Comparison Tool.
Same Game Parlay odds correct at time of publishing.
Roma vs Real Madrid Talking Points
The subplot writes itself. Mourinho returns to the Stadio Olimpico to face the club he led to the Europa Conference League title, and he is not selling sentiment. "In those 90 minutes, I want Real Madrid to win and Roma want Roma to win. At that moment, love is forgotten," he said in Rome. Mbappé is also set to make his 100th Champions League appearance, and he would be the youngest player in the competition's history to reach that mark. A big stage and a big milestone for the forward both point the same way as our Roma vs Real Madrid best picks.
Roma vs Real Madrid Predictions FAQs
When is the Roma vs Real Madrid Champions League game?
The game takes place on Wednesday, October 14, 2026, kicking off at 3:00 PM ET / 12:00 PM PT.
Where is Roma vs Real Madrid being played?
The game will be played at Stadio Olimpico in Rome.
Where can I watch Roma vs Real Madrid?
The game is scheduled to be televised on ESPN and TNT Sports 4.
What are the probable lineups for Roma vs Real Madrid?
Roma's probable lineup includes P. Gollini, G. Mancini, P. Dybala, and D. Malen. Real Madrid are expected to start T. Courtois, J. Bellingham, V. Júnior, and K. Mbappé.
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