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Roma vs Genoa Lineups, Prediction, Betting Picks & Odds

Roma vs Genoa Lineups, Prediction, Betting Picks & Odds

Roma vs Genoa prediction, probable lineups, Same Game Parlay picks and betting odds for Saturday's Serie A game. Find the key betting angles here now.

Roma vs Genoa Game Preview

Competition

Italian Serie A

Game Date

Saturday, October 17, 2026

Game Time

2:45 PM ET / 11:45 AM PT

Venue (City, Stadium)

Rome, Stadio Olimpico

Roma host Genoa at the Stadio Olimpico in Serie A on Saturday, and our Roma vs Genoa prediction starts from a simple point: the hosts carry far more firepower.

Roma sit near the top of the Serie A standings but arrive with a sting. They lost 4-3 at home to Real Madrid in the Champions League last time out.

Daniele De Rossi heads back to the Stadio Olimpico, where he played for, captained and coached Roma. His Genoa side come in fresh off their first Serie A win of the campaign.

History leans hard toward the hosts. Roma have won 17 of their last 19 home games against Genoa in all competitions. Little wonder Genoa sit at +600 (Polymarket) on the moneyline.

Roma vs Genoa Recent Results

Roma are undefeated in their last 13 games in Serie A, and Gian Piero Gasperini's side do their damage going forward, creating and finishing chances at a high level. Matías Soulé and Santiago Castro lead that attack. Europe exposed the back line, though, as Real Madrid scored three goals in the closing minutes to win their Champions League meeting.

Genoa sit near the bottom of the Serie A standings and have struggled to find consistency this season. Milutin Osmajic has still been a bright spot, finding the back of the net three times across his past four Serie A outings, while former Roma man Tommaso Baldanzi adds some craft in midfield.

Roma vs Genoa Lineups & Team News

Injuries & Suspensions

Roma: Mile Svilar (Injured/out), Bryan Cristante (Injured/doubtful), Paulo Dybala (Injured/doubtful), Donyell Malen (Suspended)

Genoa: Joi Nuredini (Injured/out), Lorenzo Colombo (Injured/out), Alex Amorim (Injured/doubtful), Lorenzo Venturino (Injured/doubtful), Djibril Sow (Injured/doubtful), Ethan Meichtry (Injured/doubtful)

Roma

The probable Roma vs Genoa lineups have the hosts in a 3-4-2-1, with Pierluigi Gollini in goal because Mile Svilar is injured. Donyell Malen is suspended and Bryan Cristante and Paulo Dybala are doubtful, so Matías Soulé and Rodrigo Mora are probable to start behind Santiago Castro.

Genoa

Daniele De Rossi goes with a probable 3-5-2, with Justin Bijlow in goal and Milutin Osmajic partnering Vitinha up front. Joi Nuredini and Lorenzo Colombo are injured, while Alex Amorim, Lorenzo Venturino, Djibril Sow and Ethan Meichtry are all doubtful.

Roma vs Genoa Predicted Lineup

Roma

Formation: 3-4-2-1

Predicted Starting Lineup: Pierluigi Gollini, Daniele Ghilardi, Leonardo Balerdi, Mario Hermoso, Wesley, Niccolò Pisilli, Marten de Roon, Emanuele Lulli, Matías Soulé, Rodrigo Mora, Santiago Castro

Genoa

Formation: 3-5-2

Predicted Starting Lineup: Justin Bijlow, Alessandro Marcandalli, Leo Østigård, Johan Vásquez, Mikael Ellertsson, Hamed Traoré, Morten Frendrup, Tommaso Baldanzi, Kingsley Ehizibue, Milutin Osmajic, Vitinha

Roma vs Genoa Key Stats & Game Facts

  • Roma have received 3+ cards in 5 of their last 7 games vs Genoa (Serie A).
  • Roma have scored 2+ goals in 5 of their last 6 games (Serie A).
  • Paulo Dybala has attempted 2+ shots in 9 of his last 10 appearances vs Genoa (Serie A).
  • Morten Frendrup has made 3+ tackles in 5 of his last 5 appearances vs Roma (Serie A).
  • Bryan Cristante has committed 2+ fouls in 4 of his last 4 appearances vs Genoa (Serie A).

Roma vs Genoa Prediction & Best Picks

Our Prediction

Our prediction is a 2-1 Roma win. The hosts have the better attack, with Soulé and Castro going at a Genoa back three that struggles against skillful players and through balls, and Roma's moneyline price of -163 (Polymarket) reflects that edge. Genoa still have enough in Osmajic to get on the board, so the Roma vs Genoa best picks lean toward goals.

Best Picks

Over 2.5 in the Total Goals Over/Under market. The model projects about 3.1 goals for Roma v Genoa. This one sits in the Total Goals Over/Under market, and the projection clears the line comfortably. Recent history agrees, as Roma have seen over 2.5 goals in their last 3 games against Genoa in all competitions.

Yes in the Both Teams To Score market. Genoa should find a goal against a Roma side missing Svilar in goal. This pick lives in the Both Teams To Score market. Both teams have scored in 4 of the last 4 meetings between these clubs in Serie A, and with Gollini deputizing and Roma shaky defending counter attacks, Genoa have a way in.

Roma vs Genoa Same Game Parlay

Our Roma vs Genoa same game parlay picks stack four legs: Osmajic to score, Dybala over 2.5 shots, Roma over 1.5 goals and Stefano Sabelli to be carded.

Milutin Osmajic in the Anytime Goalscorer market is the anchor. He leads the Genoa line in the probable XI and has been their most reliable source of goals in Serie A.

Paulo Dybala Over 2.5 in the Player Shots market hinges on fitness, since he's doubtful. Fit and on the field, he's cleared this shots total in five of six Serie A outings.

Over 1.5 in the Total Home Goals market fits our 2-1 call. Roma create and finish chances well, and Genoa's back line struggles against skillful attackers and through balls.

Stefano Sabelli in the To Be Shown A Card market has picked up a booking in two of his past three Serie A outings. He isn't in the probable XI, so he needs minutes.

Make sure to get the best odds on your Same Game Parlay with Oddschecker's Exclusive Same Game Parlay Comparison Tool.

Same Game Parlay odds correct at time of publishing.

Roma vs Genoa Talking Points

Ahead of the game, Daniele De Rossi called Roma an "incredibly strong side" and said structural discipline would be essential against his former club. That discipline gets tested out wide. Roma like attacking down the right, and Genoa struggle defending attacks down the wings, while the duel between Wesley and Mikael Ellertsson could decide who grabs early momentum on the flanks. If Genoa hold their shape, their long balls toward Osmajic give them a direct outlet.

Roma vs Genoa Predictions FAQs

When is the Roma vs Genoa Italian Serie A game?

The Saturday game kicks off at 2:45 PM ET / 11:45 AM PT. It is part of the Serie A 2026/2027 season.

Where is Roma vs Genoa being played?

The game is being played at Stadio Olimpico in Rome.

Who is in the probable Roma lineup for Roma vs Genoa?

Roma's probable 3-4-2-1 lineup includes Pierluigi Gollini, Daniele Ghilardi, Leonardo Balerdi, Mario Hermoso, Wesley, Niccolò Pisilli, Marten de Roon, Emanuele Lulli, Matías Soulé, Rodrigo Mora and Santiago Castro. Bryan Cristante and Paulo Dybala are listed as doubtful, and Donyell Malen is suspended.

What is the recent record between Roma and Genoa?

Roma have won 17 of their last 19 home games against Genoa in all competitions. In the recorded previous meetings, Roma have 3 wins, Genoa have 2 wins and there has been 1 tie.

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