TSG Hoffenheim vs Bayer Leverkusen Lineups, Prediction, Betting Picks & Odds

TSG Hoffenheim vs Bayer Leverkusen Game Preview

TSG Hoffenheim host Bayer Leverkusen at SNP Arena in the Bundesliga on Sunday, and both sides arrive in good spirits after Europa League wins on Thursday.

Hoffenheim sit 14th in the standings, a poor return for a side built on counter attacks and aerial muscle. Still, they have scored at least 2 goals in 5 of their last 6 Bundesliga games.

Leverkusen sit 4th and have won their last 3 Bundesliga games. Under Carles Martínez, they look sharp on the ball, with individual skill and wing play driving the attack.

History leans toward the visitors. Leverkusen hold a 4-2 edge in the previous meetings, with no ties, and both teams have scored in 6 of the last 7 meetings in the Bundesliga.

TSG Hoffenheim vs Bayer Leverkusen Recent Results

Hoffenheim made a miserable start to the Bundesliga campaign, but the mood has lifted. A 2-1 win over a struggling Borussia Mönchengladbach side was followed by a 3-0 home rout of Lyon in the Europa League, with Andrej Kramarić scoring the opener and setting up Adam Daghim and Adam Hložek. They want to stretch that run in all competitions.

Leverkusen arrive in even better shape. Wins over Freiburg and OFI Crete have them chasing a seventh straight victory in all competitions. Jonas Hofmann's first-half brace sealed a 2-0 Europa League win at OFI Crete, while Patrik Schick remains the focal point of a Bundesliga attack that rarely goes quiet.

TSG Hoffenheim vs Bayer Leverkusen Lineups & Team News

Injuries & Suspensions

TSG Hoffenheim: A. Hajdari (Injured/out), Patrick Wimmer (Injured/out), Nathan De Cat (Injured/out)

Bayer Leverkusen: K. Eichhorn (Injured/out), G. Doué (Injured/out), M. Terrier (Injured/doubtful), Christian Kofane (Unfit/out), Eliesse Ben Seghir (Unfit/out), M. Culbreath (Unfit)

TSG Hoffenheim

On the TSG Hoffenheim vs Bayer Leverkusen lineups front, the hosts get Bernardo back on the bench after he served his one-game suspension. Nathan De Cat needs surgery on a knee injury and faces a lengthy spell out, while Patrick Wimmer and A. Hajdari are also sidelined. Alexander Prass could keep his midfield spot ahead of Wouter Burger.

Bayer Leverkusen

Leverkusen expect to have Robert Andrich back in the squad. Christian Kofane and Eliesse Ben Seghir are both back in training but won't feature on Sunday, M. Terrier is doubtful, and K. Eichhorn and G. Doué remain out injured.

TSG Hoffenheim vs Bayer Leverkusen Predicted Lineup

TSG Hoffenheim

Formation: 4-4-2 (probable)

Predicted Starting Lineup: O. Baumann; V. Coufal, O. Kabak, K. Machida, M. Rots; B. Conté, L. Avdullahu, A. Prass, A. Daghim; T. Lemperle, F. Asllani (probable XI)

Bayer Leverkusen

Formation: 4-2-3-1 (probable)

Predicted Starting Lineup: M. Flekken; J. Quansah, E. Tapsoba, F. Medina, M. Gutiérrez; E. Fernández, A. García; M. Diaby, I. Maza, A. Moreira; P. Schick (probable XI)

TSG Hoffenheim vs Bayer Leverkusen Key Stats & Game Facts

• There have been 12+ shots on target in 4 of the last 6 meetings between Bayer Leverkusen and Hoffenheim in the Bundesliga.
• Bayer Leverkusen have scored 2+ goals in 6 of their last 6 games in the Bundesliga.
• Patrik Schick has scored in 6 of his last 6 appearances in the Bundesliga.
• Wouter Burger has been carded in 3 of his last 4 appearances in the Bundesliga.
• Bernardo has made 4+ tackles in 4 of his last 5 appearances against Bayer Leverkusen in the Bundesliga.

TSG Hoffenheim vs Bayer Leverkusen Prediction & Best Picks

Our Prediction

Our TSG Hoffenheim vs Bayer Leverkusen prediction is a 2-1 win for the visitors. Hoffenheim's counter attacks give them enough to get on the scoresheet, but they struggle to stop opponents creating looks and rarely protect a lead. Leverkusen create through individual skill and attack down the wings, and with Patrik Schick leading the line and Moussa Diaby on the right, they simply have more ways to hurt this defense.

Best Picks

Bayer Leverkusen to win at TSG Hoffenheim in the Moneyline market. Leverkusen are the side to back here. The projections hand them about a 51% win probability, well clear of the hosts, and they've taken 7 of their last 10 games against all opponents. That edge on the flanks is the reason to side with the visitors on the moneyline.

Moussa Diaby to have over 2.5 shots in the Player Shots market. Diaby is projected to start on the right of Leverkusen's attacking line, and he's gotten a shot on target in each of his past four outings against this opponent. A Leverkusen-led, high-event game should keep the looks coming his way.

TSG Hoffenheim vs Bayer Leverkusen Same Game Parlay

This Same Game Parlay backs Patrik Schick to score and to rack up shots, Leverkusen to find the net multiple times, and Wouter Burger to be carded.

Patrik Schick in the Anytime Goalscorer market is the anchor. The striker hasn't missed a Bundesliga game without scoring all season, and Hoffenheim's leaky back line is no place to expect that run to stop.

Schick Over 3.5 in the Player Shots market follows naturally. He's gotten off 4 or more attempts in five of his six league outings, and Leverkusen's wide service keeps feeding him.

Over 1.5 in the Total Away Goals market backs the visitors' attack. Leverkusen have found the net multiple times in every one of their last six league games, and Hoffenheim struggle defensively.

Wouter Burger in the To Be Shown A Card market rounds it off. The referee's book has found him three times across his past four league appearances, though Alexander Prass could keep him out of the starting lineup.

Make sure to get the best odds on your Same Game Parlay with Oddschecker's Exclusive Same Game Parlay Comparison Tool.

Same Game Parlay odds correct at time of publishing.

TSG Hoffenheim vs Bayer Leverkusen Talking Points

Christian Ilzer did not hide the brief, saying, "We want to break Leverkusen's momentum." That is a tall order against a side on a long winning run. The TSG Hoffenheim vs Bayer Leverkusen betting odds lean toward the visitors, and the flanks explain why. Leverkusen thrive attacking down the wings, while Hoffenheim rate poorly at defending wide attacks and protecting a lead, so Moussa Diaby running at Rots is the duel to watch. Expect volume, too, because both clubs trail only Bayern Munich in the Bundesliga for total shots this season.

TSG Hoffenheim vs Bayer Leverkusen Predictions FAQs

When is TSG Hoffenheim vs Bayer Leverkusen?

Kickoff is 10:30 AM ET / 7:30 AM PT on Sunday, October 25, 2026, in the 2026/2027 Bundesliga season.

Where is TSG Hoffenheim vs Bayer Leverkusen being played?

The game is being played at SNP Arena.

What are the probable lineups for TSG Hoffenheim vs Bayer Leverkusen?

Hoffenheim are expected to line up in a 4-4-2 with O. Baumann, M. Rots, O. Kabak, K. Machida, V. Coufal, A. Daghim, A. Prass, L. Avdullahu, B. Conté, T. Lemperle and F. Asllani. Leverkusen's probable 4-2-3-1 features M. Flekken, M. Gutiérrez, E. Tapsoba, F. Medina, J. Quansah, E. Fernández, A. García, A. Moreira, I. Maza, M. Diaby and P. Schick.

What is the recent form for TSG Hoffenheim vs Bayer Leverkusen?

Leverkusen have won their last 3 Bundesliga games and have scored at least 2 goals in their last 6. Hoffenheim have scored at least 2 goals in 5 of their last 6 Bundesliga games.

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