Inter Miami vs Charlotte FC Lineups, Prediction, Betting Picks & Odds

Inter Miami vs Charlotte FC Game Preview

Inter Miami host Charlotte FC at Nu Stadium in a Major League Soccer matchup that puts two of the Eastern Conference's most dangerous attacks on the same field.

Inter Miami sit second in the Eastern Conference with their playoff spot already clinched, and the Inter Miami vs Charlotte FC betting odds make them clear favorites at -250 (Polymarket).

Charlotte FC sit fifth in the East and still have plenty to play for. A win, plus help elsewhere, could carry them past the Chicago Fire for home-field advantage in the playoffs.

That gives the visitors real motivation, but they arrive shorthanded, and the moneyline prices them at +650 (Bet365) to spoil Miami's afternoon.

Inter Miami vs Charlotte FC Recent Results

Inter Miami arrive on a high after Lionel Messi's late strike sealed a 2-1 comeback win over the New England Revolution. That result made it four wins from their last six MLS outings. The attack is the headline act, with Miami leading the league in scoring, and Messi remains the man who decides these games.

Charlotte FC are every bit as hot after dismantling Orlando City 4-0 last time out. They have scored at least two goals in each of their last four MLS games, and Abdoulaye Doucouré chipped in off the bench in that rout. This is a confident group that is finishing strong.

Inter Miami vs Charlotte FC Lineups & Team News

Injuries & Suspensions

Inter Miami: Mateo Silvetti (Injured/out), Tadeo Allende (Injured/out), Fricio Caicedo (Injured/out)

Charlotte FC: Archie Goodwin (Injured/out), Brandt Bronico (Injured/out), Tim Ream (Injured/out), Aron John (Injured/out), Idan Toklomati (Injured/doubtful), Liel Abada (Injured/doubtful), Allan Saint-Maximin (Suspended)

Inter Miami

Luis Suárez, David Ayala and Sergio Reguilón could all be recalled for this one. Miami have three confirmed absentees, but none of them touches the front line, so Messi and Suárez look set to lead the attack again.

Charlotte FC

Allan Saint-Maximin is suspended for the trip to Miami after his red card against Orlando City. Liel Abada and Idan Toklomati are unlikely to be risked after picking up knocks in that game, while Abdoulaye Doucouré should start in central midfield after scoring from the bench last time out.

Inter Miami vs Charlotte FC Predicted Lineup

Inter Miami

Formation: 4-3-3 (probable)

Predicted Starting Lineup: Probable XI: Dayne St. Clair; Ian Fray, Casemiro, Micael, Sergio Reguilón; Rodrigo De Paul, David Ayala, Telasco Segovia; Lionel Messi, Luis Suárez, Germán Berterame

Charlotte FC

Formation: 4-3-3 (probable)

Predicted Starting Lineup: Probable XI: Kristijan Kahlina; Nathan Byrne, Henry Kessler, Morrison Agyemang, Harry Toffolo; Abdoulaye Doucouré, Pep Biel, Ashley Westwood; Rodolfo Aloko, Tyger Smalls, Luca de la Torre

Inter Miami vs Charlotte FC Key Stats & Game Facts

• Inter Miami have received 4+ cards in 4 of their last 5 games against Charlotte FC in Major League Soccer.
• There have been 29+ shots taken in 9 of Charlotte FC's last 10 games in Major League Soccer.
• Idan Toklomati, a doubt for this one, has scored in 5 of his last 6 Major League Soccer appearances.
• Allan Saint-Maximin, suspended here, has recorded 1+ shots on target in 9 of his last 9 Major League Soccer appearances.
• Wilfried Zaha has won 2+ fouls in 10 of his last 10 Major League Soccer appearances.

Inter Miami vs Charlotte FC Prediction & Best Picks

Our Prediction

Our Inter Miami vs Charlotte FC prediction is a Miami win, and it is not a tough call. Messi, Suárez and Berterame give the hosts the most dangerous front three on the field, while Charlotte show up without Tim Ream at the back and without the suspended Saint-Maximin up top. Charlotte also struggle to stop opponents from creating chances, which is exactly what Miami do best. Our numbers make Miami a 64.68% favorite, and that lines up with their -250 (Polymarket) price on the moneyline.

Best Picks

Over 3.5 goals in the Total Goals Over/Under market. Inter Miami's attack should drive a high-scoring afternoon. Goals are the first angle in our Inter Miami vs Charlotte FC best picks. Our numbers project 3.95 total goals, and Miami have seen over 2.5 goals in 13 of their last 16 MLS games, so clearing this line is well within reach for two attacks this sharp.

Inter Miami to win in the Moneyline market. They are the clear home favorites against a Charlotte side missing several players. This is the Moneyline market, and the home side's case is a strong one. Inter Miami are undefeated in their last 5 home games against Charlotte FC in all competitions, and the visitors are down four injured players, a suspended forward and two more doubts. The price is short, but neither the tie nor a Charlotte win fits how we see this one playing out.

Inter Miami vs Charlotte FC Same Game Parlay

Our Inter Miami vs Charlotte FC same game parlay picks lean on Messi and goals: Messi to score, Messi over 3.5 shots, over 3.5 total goals and Telasco Segovia to be carded.

Lionel Messi in the Anytime Goalscorer market is the anchor leg. Across his last 9 Major League Soccer appearances, he has scored in 6, and he gets a defense that leaks chances.

Messi Over 3.5 in the Player Shots market fits his volume. He has attempted 4+ shots in 5 of his last 6 Major League Soccer appearances, and Miami run everything through him.

Over 3.5 total goals follows the Charlotte trend too. There have been over 2.5 goals in each of their last 6 MLS games.

Telasco Segovia To Be Shown A Card rounds it off. Looking at his last 3 Major League Soccer appearances against Charlotte FC, the midfielder has been carded in 2 of them.

Make sure to get the best odds on your Same Game Parlay with Oddschecker's Exclusive Same Game Parlay Comparison Tool.

Same Game Parlay odds correct at time of publishing.

Inter Miami vs Charlotte FC Talking Points

Everything starts with Messi. The Miami captain leads the club with 26 goals and also shares the team lead in assists, so Charlotte have to deal with him as both finisher and creator. The catch for Miami is at the other end. They are poor at defending counter attacks and at stopping opponents from creating chances, and Charlotte like to play with width and go long. Their late-season surge leaned on Pep Biel and Idan Toklomati, and with Toklomati a doubt, more falls on Biel. That is why we expect goals at both ends, even with Miami the stronger side.

Inter Miami vs Charlotte FC Predictions FAQs

When is the Inter Miami vs Charlotte FC US MLS game?

The game kicks off at 4:00 PM ET / 1:00 PM PT on Saturday, November 7, 2026.

Where is Inter Miami vs Charlotte FC being played?

The game is being played at Nu Stadium.

Where can I watch Inter Miami vs Charlotte FC?

The game can be watched on Apple TV.

What formation are Inter Miami and Charlotte FC expected to use?

Both teams have a probable formation of 4-3-3 for the game.

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