Stefanos Tsitsipas vs. Novak Djokovic Prediction, Betting Pick, Latest Wimbledon Odds for Wednesday's Second Round
Novak Djokovic and Stefanos Tsitsipas meet Wednesday, July 1, in a Wimbledon second-round matchup between two players at very different stages of their careers. Djokovic remains one of the most reliable Grand Slam forces in tennis, while Tsitsipas is trying to rediscover the level that once made him a top-five player.
Peter Alexis - July 1, 2026, 9:55 AM EDT
4 Minute ReadStefanos Tsitsipas vs. Novak Djokovic Prediction: Can Djokovic Extend 11-Match Win Streak Against Tsitsipas in Wimbledon Second Round?
Novak Djokovic faces Stefanos Tsitsipas on Wednesday, July 1, at 12:15 p.m. ET in the second round at Wimbledon. The match brings one of the tournament’s most decorated players back onto the grass against a former Grand Slam finalist still searching for consistency.
Djokovic is a -600 favorite, while Tsitsipas is listed at +450. The price reflects both Djokovic’s long-running dominance in the matchup and the current gap between the two, even with Djokovic now deep into the back end of his career.
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Stefanos Tsitsipas vs. Novak Djokovic Odds
- Moneyline: Tsitsipas (+450), Djokovic (-600)
Stefanos Tsitsipas vs. Novak Djokovic Date, Time, and Where to Watch
- Date: Wednesday, July 1st, 2026
- Time: 12:30 PM ET
- Where to Watch: ESPN
Click here for complete Stefanos Tsitsipas vs. Novak Djokovic Odds
Stefanos Tsitsipas vs. Novak Djokovic Prediction
Djokovic has won 11 straight matches against Tsitsipas after the Greek took two of their first three meetings back in 2018. The overall head-to-head is now 12-2, and that history matters because Djokovic has repeatedly solved Tsitsipas’ patterns in the biggest moments. He has handled the one-handed backhand matchup, absorbed the forehand pressure, and forced Tsitsipas to play cleaner for longer than he usually can.
Tsitsipas’ current form is the bigger concern. He was once one of the fastest risers in tennis, reaching the top five and looking like a future Grand Slam champion before his career stalled. Now ranked outside the top 80, he still has the serve, forehand and athleticism to challenge elite players in stretches, but the week-to-week reliability has not been there for a long time.
Djokovic is aging, but his Grand Slam floor remains extremely high. He was pushed in his first-round win over Wu Yibing, dropping a set and having to manage some uncomfortable moments, but that also fits the late-career Djokovic profile. He may not dominate every minute, yet he still knows how to raise his level in the decisive parts of sets and avoid letting matches spiral.
The best-of-five format is what makes this market interesting. Djokovic can be the clear winner and still drop a set, especially against a talented underdog who can serve well for a stretch and steal one tiebreak-style frame. Tsitsipas does not need to win the match for this angle to work, he only needs to find one strong set before Djokovic’s consistency and return pressure take over.
Stefanos Tsitsipas vs. Novak Djokovic Best Bet
- Best Bet: Tsitsipas To Win At Least One Set And Djokovic ML (+120) Check out the best odds at FanDuel Sportsbook
Back Tsitsipas to win at least one set and Djokovic to win the match at +120. Djokovic’s head-to-head dominance and Grand Slam reliability make the upset difficult to trust, but Tsitsipas still has enough shot-making to avoid a clean sweep. This is the kind of major-market combo that benefits from the favorite needing three full sets to close, while the underdog has enough talent to steal one without changing the final result.
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