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Bayer Leverkusen vs RB Leipzig: Lineups, Prediction, Betting Tips & Odds

Bayer Leverkusen vs RB Leipzig: Lineups, Prediction, Betting Tips & Odds
James Smith | 09:42 Sunday 20th September 2026

Get the latest Bayer Leverkusen vs RB Leipzig prediction, betting tips, lineups, and odds ahead of this crucial German Bundesliga clash at BayArena.

Bayer Leverkusen vs RB Leipzig Match Summary

Competition

German Bundesliga

Match Date

Sunday 20 September 2026

Match Time

14:30 UK time

Venue (City, Stadium)

Leverkusen, BayArena

Broadcast (TV / Streaming / Radio / Bookmaker Streaming)

Sky Calcio

The German Bundesliga serves up a heavyweight fixture as Bayer Leverkusen host RB Leipzig at the BayArena, and this Bayer Leverkusen vs RB Leipzig prediction points to another goal-laden afternoon.

Leverkusen come in having won just one of their opening three league outings, taking a win, a draw and a defeat, but they remain the marginal favourites in front of their own supporters.

Leipzig arrive full of belief after banking six points from their first three matches, sitting fifth in the table and fresh from a thumping display last time out.

These two rarely disappoint for entertainment, with Leverkusen having scored at least two goals in each of their last seven meetings with Leipzig in all competitions.

Bayer Leverkusen vs RB Leipzig Form

Die Werkself have been a touch messy domestically, with one win from three, though they salvaged a 2-2 draw at Augsburg thanks to Patrik Schick's 89th-minute equaliser. The Czech striker is red hot, scoring in each of his last three Bundesliga outings. In Europe they were more assured, cruising to a 2-0 home win over NK Celje in the Europa League.

Leipzig have found their stride, responding to back-to-back defeats by hammering Hamburg 5-0, with five different names on the scoresheet. Six points from three games has them fifth and looking dangerous going forward. Christopher Nkunku carries a real threat, having scored or assisted in four of his last five appearances against Leverkusen in the Bundesliga.

Bayer Leverkusen vs RB Leipzig Lineups & Team News

Injuries & Suspensions

Bayer Leverkusen: M. Culbreath (Injured/out), K. Eichhorn (Injured/out), Guela Doue (Injured/out), Ibrahim Maza (Injured/doubtful), N. Tella (Unfit)

RB Leipzig: Assan Ouedraogo (Injured/out), Rocco Reitz (Unfit), Christoph Baumgartner (Unfit)

Bayer Leverkusen

Leverkusen will make a late call on Ibrahim Maza's fitness, leaving his place in doubt, while Guela Doue is sidelined for several weeks with a muscle injury. There is a boost in that Eliesse Ben Seghir made his return in the Europa League on Wednesday.

RB Leipzig

Leipzig are without Assan Ouedraogo, who could be out until 2027 after a serious injury against Hamburg. Rocco Reitz and Christoph Baumgartner are back in training but won't feature here, so Leipzig largely stick with the side that ran riot last week.

Bayer Leverkusen vs RB Leipzig Predicted Lineup

Bayer Leverkusen

Formation: 4-2-3-1

Predicted Starting Lineup: Flekken; Gutiérrez, Tapsoba, Medina, Quansah; Fernández, García; Moreira, Maza, Diaby; Schick

RB Leipzig

Formation: 4-3-3

Predicted Starting Lineup: Vandevoordt; Raum, Lukeba, Orbán, Baku; El Aynaoui, Banzuzi, Gruda; Nusa, Nkunku, Gomis

Check out all the latest oddschecker Free Bets & Sign-Up Offers for Bayer Leverkusen vs RB Leipzig.

Bayer Leverkusen vs RB Leipzig Key Stats & Match Facts

  • Bayer Leverkusen have scored 2+ goals in 7 out of 7 matches vs RB Leipzig (Bundesliga).

  • There have been 4+ goals scored in 6 of the last 6 meetings between Bayer Leverkusen vs RB Leipzig (Bundesliga).

  • Both teams have scored in 6 of the last 6 meetings between Bayer Leverkusen vs RB Leipzig (Bundesliga).

  • There have been over 2.5 goals scored in 7 of Leverkusen's last 8 games in the Bundesliga.

  • Patrik Schick has attempted 4+ shots in 3 of his last 3 appearances in the Bundesliga.

Bayer Leverkusen vs RB Leipzig Prediction & Best Bets

Our prediction: Everything about this fixture screams goals, and the model points to a 2-2 draw. Leverkusen are the home favourites at 10/11 (Coral), but Leipzig carry enough firepower to make life difficult, and with both teams scoring in each of the last six meetings, backing goals across the board looks the sensible route in these Bayer Leverkusen vs RB Leipzig best bets.

Best Bets

Neil El Aynaoui to record Over 1.5 shots in the Player Shots market. The Leipzig midfielder carries a strong AI-projected probability to attempt at least two shots in what shapes up as a high-tempo contest, and his advancing role from the engine room means he should get himself into shooting positions against a Leverkusen side that ships chances through the middle.

Aleix Garcia to record Over 0.5 shots on target in the Player Shots On Target market. Leverkusen's midfield orchestrator and dead-ball specialist rates well to test Vandevoordt, and with the home side firing off plenty of efforts, their set-piece taker looks a smart pick to hit the target in support of the favourites.

Bayer Leverkusen vs RB Leipzig Bet Builder

Our four-leg Bayer Leverkusen vs RB Leipzig bet builder tips lean into the goals theme: Patrik Schick anytime scorer, Schick over 3.5 shots, over 1.5 Leverkusen goals, and Christopher Nkunku over 0.5 shots on target.

Schick is the obvious anchor. The striker has found the net in each of his last three Bundesliga appearances and is thriving in front of goal for the hosts.

The shots leg follows naturally, with Schick having attempted 4+ shots in three of his last three Bundesliga outings, so he should keep testing the Leipzig goalkeeper.

Backing over 1.5 Leverkusen goals looks solid too, given they have scored 2+ goals in seven of seven meetings with Leipzig in the Bundesliga.

Nkunku completes it as a live threat leading the line, having recorded 1+ shots on target in six of his last eight appearances against Leverkusen in the Bundesliga.

At the time of writing, this bet builder pays a best price of 3/1 and is as short as 11/5 elsewhere.

Make sure to get the best odds on your Bet Builder with Oddschecker's Exclusive Bet Builder Comparison Tool.

Bet builder odds correct at time of publishing.

Bayer Leverkusen vs RB Leipzig Talking Points

This one has history for chaos. There have been over 2.5 goals in each of the last six meetings between these two in all competitions, and with both squads carrying attacking punch, few would bet against another open affair. Leverkusen love to attack down the wings and from set pieces, but they are vulnerable through the middle, which plays right into the hands of a Leipzig outfit brimming with individual quality. David Raum and Ridle Baku were both called up to the Germany squad in September, underlining the depth Leipzig have to work with. Expect end-to-end football and goals at both ends.

Bayer Leverkusen vs RB Leipzig Predictions FAQs

When is the Bayer Leverkusen vs RB Leipzig German Bundesliga game?

The match takes place on Sunday, 20 September 2026, kicking off at 14:30 UK time.

Where is Bayer Leverkusen vs RB Leipzig being played?

The match is being played at BayArena in Leverkusen.

Where can I watch Bayer Leverkusen vs RB Leipzig?

The match is scheduled to be broadcast live on Sky Calcio.

What competition is Bayer Leverkusen vs RB Leipzig in?

The fixture is part of the German Bundesliga.

Disclaimer

Important information: This article may contain links to betting offers or promotions for Bayer Leverkusen vs RB Leipzig that were available at the time of publication. These offers may have since expired, changed, or no longer be available.

Oddschecker offers are selected from operators that our football experts work with regularly and have first-hand experience of. If you open an account via one of these links, Oddschecker may earn commission. This helps support our coverage and allows us to continue producing expert analysis and football content across German Bundesliga.

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