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Dodgers Shohei Ohtani Run

World Series Odds: Dodgers, Phillies Still Biggest World Series Favorites as MLB Playoffs Begin

The Los Angeles Dodgers look destined to repeat their World Series title in 2025 with a dominant offensive showing to start off the playoffs. Can anyone contend with Shohei Ohtani and the Dodgers firepower? The Phillies are in the mix of a stacked NL bracket. Peter Alexis takes a look at the latest World Series odds as the opening round of the MLB Playoffs commences.

Peter Alexis - October 1, 2025, 3:00 AM EDT

4 Minute Read

World Series Odds: Can Anyone Stop Shohei Ohtani, Dodgers from Repeating in 2025?

The MLB playoffs are officially underway, and October baseball is here with the chase for the World Series just weeks away. The postseason promises intense matchups, and fans are already looking at the favorites and dark horses who could make a deep run. Heading into the playoffs, the Los Angeles Dodgers (+370) and Philadelphia Phillies (+450) are perched atop the odds, boasting both star power and depth to contend for a championship.

Los Angeles is looking to repeat after a thrilling 2024 season, while Philadelphia hopes to finally go all the way after falling short in previous campaigns. Both teams have proven they can handle pressure, and their rosters are filled with proven performers capable of delivering in October. But other teams like the Mariners and Blue Jays are quietly making noise, ready to challenge the favorites in what could be one of the most unpredictable postseasons in recent years. Let’s take a closer look at the latest World Series odds and break down the top contenders for 2025.

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World Series Odds

MLB World Series Odds

1. Los Angeles Dodgers +370

The Dodgers won the NL West in a tight race over the Padres that came down to the final days of the season. They are going for a repeat, taking on the wild card Cincinnati Reds in the opening round. Shohei Ohtani leads the way, supported by stars like Mookie Betts and Freddie Freeman, giving Los Angeles the firepower to make another deep playoff run.

2. Philadelphia Phillies +450

Philadelphia captured the NL East by a wide margin and are seeking redemption after falling short in the 2022 World Series. The Phillies have retained most of their core players, like Bryce Harper and Kyle Schwarber, and are poised to contend for a championship in 2025, combining pitching depth with a potent lineup that can challenge any opponent.

3. Seattle Mariners +500

The Mariners are an unusual contender, often falling short in playoff races over the years. But this season, Cal Raleigh smashed the record for home runs by a catcher and set a new franchise mark at 60, helping Seattle win their first AL West title since 2001. The Mariners hope to translate this success into a meaningful postseason run.

4. Toronto Blue Jays +800

The Blue Jays quietly dominated the AL East in 2025, taking over the division from the Yankees and finishing with 94 wins. Vlad Guerrero Jr. anchors a balanced lineup, and Toronto will rely on both their offense and pitching depth to make a push through October and into the later rounds of the playoffs.

MLB ODDS

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