Vegas March Madness Odds: Betting Lines for Every Round of 64 Game on Thursday

Oddschecker analyst Peter Alexis breaks down the latest Vegas March Madness odds. Come check out the March Madness betting line for every game in Thursday's Round of 64.

Peter Alexis - March 20, 2024, 7:00 PM EDT

8 min

Vegas March Madness Odds: Betting Lines for Every Round of 64 Game on Thursday

The First Four has brought some interesting results, and now the field is set for the Round of 64. March Madness officially tips off on Thursday afternoon with 16 exciting matchups.

Let's take a look at the latest Vegas March Madness odds for the Round of 64 games on Thursday.

Looking for over $5,000 worth of sports betting bonuses to use on March Madness? Click here and get that with our free bets page!

Round of 64 Vegas March Madness Odds

Vegas March Madness Odds: (9) Michigan State vs. (8) Mississippi State Odds

Date: March 21, 2024
Start Time: 12:15 pm ET
Moneyline: Michigan State -120, Mississippi State +100
Spread: Michigan State -1
Total: O/U 130.5

Click here for Michigan State vs. Mississippi State odds

Vegas March Madness Odds: (11) Duquesne vs. (6) BYU Odds

Date: March 21, 2024
Start Time: 12:40 pm ET
Moneyline: BYU -485, Duquesne +370
Spread: BYU -9.5
Total: O/U 142

Click here for Duquesne vs. BYU Odds

Vegas March Madness Odds: (14) Akron vs. (3) Creighton Odds

Date: March 21, 2024
Start Time: 1:30 pm ET
Moneyline: Creighton -900, Akron +600
Spread: Creighton -12.5
Total: O/U 141

Click here for Akron vs. Creighton Odds

Vegas March Madness Odds: (15) Long Beach State vs. (2) Arizona Odds

Date: March 21, 2024
Start Time: 2:00 pm ET
Moneyline: Arizona -3600, Long Beach State +1500
Spread: Arizona -20.5
Total: O/U 163.5

Click here for Long Beach State vs. Arizona Odds

Vegas March Madness Odds: (16) Wagner vs. (1) North Carolina Odds

Date: March 21, 2024
Start Time: 2:45 pm ET
Moneyline: North Carolina -6500, Wagner +2000
Spread: North Carolina -25.5
Total: O/U 133.5

Click here for Wagner vs. North Carolina Odds

Vegas March Madness Odds: (14) Morehead State vs. (3) Illinois Odds

Date: March 21, 2024
Start Time: 3:10 pm ET
Moneyline: Illinois -850, Morehead State +575
Spread: Illinois -11.5
Total: O/U 147.5

Click here for Morehead State vs. Illinois Odds

Vegas March Madness Odds: (11) Oregon vs. (6) South Carolina Odds

Date: March 21, 2024
Start Time: 4:00 pm ET
Moneyline: South Carolina -115, Oregon -105
Spread: South Carolina -1.5
Total: O/U 133.5

Click here for Oregon vs. South Carolina Odds

Vegas March Madness Odds: (10) Nevada vs. (7) Dayton Odds

Date: March 21, 2024
Start Time: 4:30 pm ET
Moneyline: Nevada -120, Dayton +100
Spread: Nevada -1.5
Total: O/U 136.5

Click here for Nevada vs. Dayton Odds

Vegas March Madness Odds: (10) Colorado State vs. (7) Texas Odds

Date: March 21, 2024
Start Time: 6:50 pm ET
Moneyline: Texas -145, Colorado State +125
Spread: Texas -2.5
Total: O/U 144

Click here for Colorado State vs. Texas Odds

Vegas March Madness Odds: (14) Oakland vs. (3) Kentucky Odds

Date: March 21, 2024
Start Time: 7:10 pm ET
Moneyline: Kentucky -1100, Oakland +700
Spread: Kentucky -13.5
Total: O/U 163.5

Click here for Oakland vs. Kentucky Odds

Vegas March Madness Odds: (12) McNeese vs. (5) Gonzaga Odds

Date: March 21, 2024
Start Time: 7:25 pm ET
Moneyline: Gonzaga -275, McNeese +225
Spread: Gonzaga -6.5
Total: O/U 150

Click here for McNeese vs. Gonzaga Odds

Vegas March Madness Odds: (15) South Dakota State vs. (2) Iowa State Odds

Date: March 21, 2024
Start Time: 7:35 pm ET
Moneyline: Iowa State -1650, South Dakota State +950
Spread: Iowa State -16
Total: O/U 135.5

Click here for South Dakota State vs. Iowa State Odds

Vegas March Madness Odds: (15) Saint Peter's vs. (2) Tennessee Odds

Date: March 21, 2024
Start Time: 9:20 pm ET
Moneyline: Tennessee -4000, Saint Peter's +1600
Spread: Tennessee -21.5
Total: O/U 130

Click here for Saint Peter's vs. Tennessee Odds

Vegas March Madness Odds: (11) NC State vs. (6) Texas Tech Odds

Date: March 21, 2024
Start Time: 9:40 pm ET
Moneyline: Texas Tech -220, NC State +180
Spread: Texas Tech -5
Total: O/U 145.5

Click here for NC State vs. Texas Tech Odds

Vegas March Madness Odds: (13) Samford vs. (4) Kansas Odds

Date: March 21, 2024
Start Time: 9:55 pm ET
Moneyline: Kansas -280, Samford +230
Spread: Kansas -7
Total: O/U 153.5

Click here for Samford vs. Kansas Odds

Vegas March Madness Odds: (10) Drake vs. (7) Washington State Odds

Date: March 21, 2024
Start Time: 10:05 pm ET
Moneyline: Drake -125, Washington State +105
Spread: Drake -1.5
Total: O/U 137.5

Click here for Drake vs. Washington State Odds

COLLEGE BASKETBALL ODDS

Join the oddschecker Community

Bet with Intelligence

Sign-up for an oddschecker account to get expert picks, ai-driven betting tools and best odds across sportsbooks.

Insight

Last Chance to Claim the DraftKings $200 Promo Code for UFC Freedom 250

This is the Last chance to claim the DraftKings Bet $5, Get $200 bonus before UFC Freedom 250 begins. Get the latest odds for Topuria, Gaethje, Pereira, O’Malley, and more, plus how to watch and how to use your $200 Bonus Bets on tonight’s card.

Oliver Leonard

June 14, 2026, 5:00 PM EDT

3 Minute Read

Kalshi with a green background on a phone

Kalshi Promo Code ODDSCHECKER: Trade $10, Get $10 on Topuria vs Gaethje, Any Other Fight on UFC Freedom 250

Lock in a $10 Kalshi bonus with code ODDSCHECKER for UFC Freedom 250. Check out active contract lines for the main card and stream tonight on Paramount+.

Oliver Leonard

June 14, 2026, 4:00 PM EDT

3 Minute Read

DraftKings UFC Freedom 250 Odds: How to Bet on Topuria v Gaethje, Pereira v Gane

Get the latest DraftKings UFC Freedom 250 odds for Topuria vs Gaethje and Pereira vs Gane, plus a full guide on how to bet the card using DraftKings’ Bet $5, Get $200 Instant Bonus.

Oliver Leonard

June 14, 2026, 3:00 PM EDT

5 Minute Read

UFC Freedom 250 Odds: How to Bet on Topuria, Gaethje, Pereira, and More

Get the latest UFC Freedom 250 odds for Topuria, Gaethje, Pereira, O’Malley, and more, plus a full breakdown of the best sportsbook promos from DraftKings, FanDuel, bet365, and BetMGM

Oliver Leonard

June 14, 2026, 12:00 PM EDT

5 Minute Read

DraftKings Promo Code: Bet $5, get $200 Instantly on Brazil vs Morocco

Claim the DraftKings promo code to Bet $5, Get $200 Instantly on today’s Brazil vs Morocco matchup. See the latest odds, first‑goalscorer prices, and the smartest ways to use your Bonus Bets before kickoff

Oliver Leonard

June 13, 2026, 4:00 PM EDT

3 Minute Read

More Insights

Picks

Alex Pereira vs. Ciryl Gane Prediction, Betting Pick, Latest Odds for UFC Freedom 250

Alex Pereira will take on Ciryl Gane tonight for UFC Freedom 250. They'll battle in a UFC main card heavyweight matchup, with Pereira the favorite. McBets is backing Pereira in this UFC matchup.

McBets

June 14, 2026, 8:50 PM EDT

4 Minute Read

Ilia Topuria vs. Justin Gaethje Prediction, Betting Pick, Latest UFC Freedom 250 Odds for Lightweight Bout

Ilia Topuria faces Justin Gaethje on Sunday, June 14, in the UFC Freedom 250 main event for the lightweight title. Can Topuria defend his belt with another statement knockout, or will Gaethje’s pressure and power create chaos? Check out this Ilia Topuria vs. Justin Gaethje prediction and best bet for UFC Freedom 250.

Peter Alexis

June 14, 2026, 6:30 PM EDT

4 Minute Read

Alex Pereira vs. Ciryl Gane Prediction, Betting Pick, Latest UFC Freedom 250 Odds for Middleweight Bout

Alex Pereira faces Ciryl Gane on Sunday, June 14, in the UFC Freedom 250 co-main event at the White House. Can Pereira complete another historic title jump, or will Gane’s heavyweight experience prove too much? Check out this Alex Pereira vs. Ciryl Gane prediction and best bet for UFC Freedom 250.

Peter Alexis

June 14, 2026, 6:00 PM EDT

4 Minute Read

Derrick Lewis vs. Josh Hokit Prediction, Betting Pick, Latest UFC Freedom 250 Odds for Heavyweight Bout

Derrick Lewis faces Josh Hokit on Sunday, June 14, in a heavyweight matchup at UFC Freedom 250. Can Lewis land another vintage knockout shot, or will Hokit’s athleticism and pressure overwhelm the veteran? Check out this Derrick Lewis vs. Josh Hokit prediction and best bet for UFC Freedom 250.

Peter Alexis

June 14, 2026, 5:45 PM EDT

4 Minute Read

Sean O’Malley vs. Aiemann Zahabi Prediction, Betting Pick, Latest UFC Freedom 250 Odds for Bantemweight Bout

Sean O’Malley takes on Aiemann Zahabi on Sunday, June 14, at UFC Freedom 250 in Washington, D.C. Can O’Malley control the fight from range and move back toward the bantamweight title picture, or will Zahabi pull off the upset? Check out this Sean O’Malley vs. Aiemann Zahabi prediction and best bet for UFC Freedom 250.

Peter Alexis

June 14, 2026, 5:35 PM EDT

4 Minute Read