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Kansas City Chiefs vs. Los Angeles Chargers Week 3 Betting Preview, Odds, and Prediction

Books opened the Kansas City Chiefs as touchdown favorites at home against the Los Angeles Chargers, but the public has bet down the NFL line by siding with the road underdogs in this blockbuster AFC West showdown.
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Kansas City Chiefs vs. Los Angeles Chargers Week 3 Betting Preview, Odds, and Prediction

Date: Sunday, September 26, 2021

Game Time: 1:00 PM ET

Location: Arrowhead Stadium, Kansas City 

TV Network: CBS

Kansas City Chiefs (1-1-0 SU, 1-1-0 ATS)

Los Angeles Chargers: (1-1-0 SU, 1-1-0 ATS)

Chiefs vs. Chargers Betting Odds 

The Kansas City Chiefs lost to the Baltimore Ravens 36-35 in primetime Sunday night football action. Similarly, the Los Angeles Chargers are flush off a 20-17 decision that went the way of the Dallas Cowboys at SoFi Stadium. Both the Chiefs and the Chargers will be keen to get back on track, but only one side will be able to do so when they collide at Arrowhead Stadium in Week 3.

Predictably, books favor the Chiefs at the expense of the Chargers in this highly-anticipated AFC West tilt. The Chiefs opened as the 7-point home chalk, but the NFL line whittled down to -6.5 with most shops by early doors. According to early consensus betting trends, the public appears to be grabbing the points with the Chargers. Moreover, the Chargers appear to be the choice bet to win straight up amongst these early birds. 

Yes, it’s early days. Sunday kick-off is some distance away, and these betting trends could shift in the opposite direction before then. But it’s frankly interesting to learn that the public is betting against Mahomes and the Chiefs in this spot. 

Kansas City Chiefs Odds & Overview

The Baltimore Ravens delivered one of the biggest upsets of the 2021 NFL season, coming from behind to beat the highly-fancied Kansas City Chiefs 36-35 at the M&T Stadium in Sunday night football. The Chiefs closed as the -3.5 road chalk, but they failed to deliver on the odds. 

Mahomes and the Chiefs jumped out to a significant lead initially. Costly errors, lack of focus, and an untimely interception in the second half proved their undoing, however. The final nail in their coffin came on the last drive, with the Chiefs trailing 36-35. Andy Reid called a rushing play, entrusting Clyde Edwards-Helaire to keep the drive going. But the running back coughed up the ball, giving the Ravens the chance to bleed the clock and clinch their first-ever win against Mahomes and the Chiefs. 

Why Reid didn’t trust his best player, Mahomes, and the passing game to deliver the final blow – as has often been the case in the past – is a head-scratcher. It could prove a big mistake because the Chiefs find themselves in a rare situation, sat third in the AFC West behind a 1-1-0 record. Yup, true story. The Chiefs are third in the standings, nipping at the heels of the Las Vegas Raiders and Denver Broncos – two of the seven teams that are undefeated going into Week 3. And getting back to the top will be challenging if the Raiders and Broncos keep up their momentum.

Los Angeles Chargers Odds & Overview

The Los Angeles Chargers were guilty of being wasteful in a 20-17 loss to the Dallas Cowboys at Sofi Stadium. Justin Herbert and Co. had many chances, but costly turnovers, interceptions, and a rash of penalties had them playing on the back foot for the better part of the game. The gut punch came in the dying minutes as a potentially game-winning touchdown was negated by an undisciplined penalty. It was the opening the Cowboys needed. 

In the end, the Chargers can only look in the mirror. The Cowboys didn’t beat them. They beat themselves. The upshot is a 1-1-0 record in the first two weeks and fourth place in the AFC West.

Kansas City Chiefs vs. Los Angeles Chargers Odds

Chargers+250+6.5Over 55 (-110)
Chiefs-275-6.5Under 55 (-105)

Click Here For Chiefs vs. Chargers Betting Odds 

Kansas City Chiefs vs. Los Angeles Chargers Betting Prediction

The first-ever meeting between Justin Herbert and Patrick Mahomes was in Week 2 of the 2020 season. It was Herbert’s NFL debut, and it was epic. He very nearly pulled off the upset too, but the Chiefs rallied from behind to take the narrow 23-20 win. Mahomes sat out the second meeting with the Chargers in Week 17, as did many starters because the playoffs were around the corner. The Chargers won comfortably.

Another close encounter between this pair - falling in line with the first-ever meeting - is possible. Early bettors appear to be hanging their hats on such an outcome. However, the reality is that Kansas City rarely suffers back-to-back losses. Therefore, the Chiefs will be motivated to win and have a home-field advantage for this crucial division clash. 

Put it another way, losing to the Chargers is not an option. Firstly, it would be an aberration that would send seismic shockwaves through the NFL. Secondly, it would also likely see the Chiefs fall to the bottom of the AFC West standings, which would tip the NFL off of its axis. 

NFL Picks: Chiefs -6.5 (-110)

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Nikki Adams is a freelance sports writer that’s honed in on the world of sports betting. She joined OddsChecker in 2021 after having covered a number of major American sports, including NFL and NCAAF, for several other publications in the industry. When she’s not looking for the best betting angles and writing engaging and insightful articles, she’s likely on a tennis court or binging on reality TV.


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