Chiefs vs Bills Odds: How to Bet on NFL Sunday with DraftKings, FanDuel, and More

Chiefs vs Bills Odds: How to Bet on NFL Sunday with DraftKings, FanDuel, and More

On Sunday evening the Kansas City Chiefs head to Orchard Park to take on the Buffalo Bills in a vital AFC-matchup at Highmark Stadium.

The Bills (5-2) have been sharp at home this season, while the Chiefs (5-3) are trying to regain momentum after a mid-season stumble.

The rivalry between QBs Josh Allen and Patrick Mahomes adds extra firepower - these two teams have met nine times since 2020, and the aggregate scoring margin is just one point (243-242).

To make the most of this matchup, several major sportsbooks including FanDuel, bet365, DraftKings, and BetMGM are offering standout new-user promos.

Here’s a breakdown of the top offers, followed by how to bet this game: popular markets, strategic angles and what to watch!

Odds for Chiefs vs Bills

Here are the latest odds for the epic NFL Sunday matchup:

• Moneyline: Chiefs -127, Bills +115
• Point Spread: Chiefs -1.5 (-110), Bills +1.5 (-102)
• Total Points (Over/Under): O52.5 (-106), U52.5 (-110)

How to Bet – Popular Betting Markets for NFL Games

• Moneyline – Pick the team you think will win outright.
• Point Spread – One team has to cover the spread (e.g., Chiefs -3 means win by 4+ points).
• Total Points (Over/Under) – Bet on whether the combined score will be over or under a set number.
• Player Props – Individual player performance bets (e.g., passing yards, rushing touchdowns, receptions).
• Same Game Parlays (SGPs) – Combine multiple picks from the same game (e.g., Chiefs ML + Over 45 + Mahomes 300+ passing yards) for a higher payout – but higher risk.
• Live Betting – After kickoff, odds shift based on momentum, big plays, injuries and game flow.

DraftKings Promo – Bet $5, Get $300 (If Your Bet Wins) + 3 Months NBA League Pass

Do you want $300 in Bonus Bets to use on this game? Follow the steps below and see how you can claim them:

Step One: CLICK HERE or go to DraftKings and register a new account.

Step Two: Deposit $5 or more into your DraftKings account.

Step Three: Place a $5 bet on any Chiefs vs Bills market.

Step Four: If your bet wins, you’ll receive $300 in bonus bets instantly.

Step Five: If your first qualifying wager is at minimum odds of -500 or longer, DraftKings will issue your NBA League Pass code instantly (good for three months of free access).

FanDuel Promo – Bet $5, Get $300

This is how you can claim FanDuel's awesome new customer promo:

Step One: CLICK HERE or visit FanDuel Sportsbook and register a new account.

Step Two: Make a deposit of at least $10.

Step Three: Wager $5 on any market – including the Chiefs vs Bills game.

Step Four: If your wager wins, you’ll receive $300 in bonus bets credited to your account.

Bet365 Promo – $200 Bonus for New Customers

New customers ate bet365 can use bonus code 'CHECK' to gain $200 in bonus bets for this matchup:

Step One: CLICK HERE or go to Bet365’s website to ensure you qualify (new customer only).

Step Two: Register a new Bet365 account using bonus code ‘CHECK’.

Step Three: Deposit $10 and place a $5 wager on any NFL market.

Step Four: If your wager wins, you’ll receive $200 in bonus bets thanks to the Bet365 promotion.

BetMGM Promo – Bet $10, Get $150 (MI/NJ/PA/WV) / First-Bet Offer Up to $1,500 (Other States)

For Michigan, New Jersey, Pennsylvania, West Virginia (Bet & Get):

Step One: CLICK HERE to register a new account at BetMGM.

Step Two: Deposit $10.

Step Three: Place your first $10 bet on any qualifying MLB/NFL/MLB market (including Chiefs vs Bills).

Step Four: If that bet wins, receive $150 in bonus bets in addition to your cash winnings.

For all other states (First-Bet Offer):

Step One: Visit BetMGM or click the offer widget; enter bonus code OCMAX1500 if prompted.

Step Two: Deposit between $10 and $1,500.

Step Three: Place your first qualifying wager (straight, parlay, SGP etc).

Step Four: If it wins: you keep your profits + original stake. If it loses: BetMGM refunds your original wager as bonus bets (up to $1,500).

Full NFL Sunday Slate – Sunday, November 2, 2025

Here are the games scheduled for this Sunday. Remember, you can also use your bonus bets to wager on any of these matchups!

• Chicago Bears @ Cincinnati Bengals - 1:00 PM ET
• Minnesota Vikings @ Detroit Lions - 1:00 PM ET
• Carolina Panthers @ Green Bay Packers - 1:00 PM ET
• Denver Broncos @ Houston Texans - 1:00 PM ET
• Atlanta Falcons @ New England Patriots - 1:00 PM ET
• San Francisco 49ers @ New York Giants - 1:00 PM ET
• Indianapolis Colts @ Pittsburgh Steelers - 1:00 PM ET
• Los Angeles Chargers @ Tennessee Titans - 1:00 PM ET
• New Orleans Saints @ Los Angeles Rams - 4:05 PM ET
• Jacksonville Jaguars @ Las Vegas Raiders - 4:05 PM ET
• Kansas City Chiefs @ Buffalo Bills - 4:25 PM ET
• Seattle Seahawks @ Washington Commanders - 8:20 PM ET