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We need a bet in this great game, look no further. Josh Gayle has you covered with the best NFL Week 6 game of the week. Come find out his NFL Chiefs vs. Bills prediction, pick, and odds.

Kansas City Chiefs vs. Buffalo Bills Prediction, Pick, Odds: Will Devin Singletary Help Bills Get Huge Win?

This game not being a primetime game feels wrong. In what will likely be a playoff preview we have the powerhouse Bills against the red-hot Chiefs. Every prop for this game is moving quickly as the public knows this one should be high scoring so let's waste no time and get this one in quick! We are on Devin Singletary to have 21+ receiving yards and although he’s only 2/5 on hitting this prop this year we have reason to be optimistic.

Chiefs vs. Bills Start Time, Where to Watch, and Odds

  • Date: October 16, 2022
  • Game Time: 4:25 pm ET
  • Where to Watch: CBS

Chiefs vs. Bills Odds

  • Spread: Bills -3 (-110), Chiefs +3 (-110)
  • Total Odds: O/U 54 (-110)
  • Moneyline Odds: Bills (-135), Chiefs (+130)

Click Here for Chiefs vs Bills Odds

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Chiefs vs. Bills Prediction

1u - Devin Singletary o20.5 Rec Yards (-115 @ MGM) (Bet $115 to win $100)

I’m a believer in game plans. When a team is up by multiple possessions, they are less likely to pass the ball because they want the clock to continue moving. Singletary has hit in two games of the five but the two games were both competitive games against the Ravens and Dolphins. Both games were decided by 3 pts or less, this game projects similarly. The three games that Singletary didn’t hit this prop were because Buffalo won by 35, 38, and 21 points. There was no reason for him to be a member of the passing game with such a lead.

In a weird way, I like this bet because I trust Mahomes and the Chiefs. Neither team should blow out the other and Kansas City has allowed a running back to hit this number in all 5 games. The Chiefs allow 70 yards a game to running backs as pass catchers which is the most in the NFL. Singletary shines in big games and these are the best two teams in my opinion. I think this bet could be laddered as well and he has a huge upside to crush this number. We’ll play it safe and just play for one unit but I love this one. Let's roll!

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Article Author


Josh has a knack for picking winning bets, and he specializes in the NFL, NBA, and MLB. As a lifelong Detroit sports fan, he has plenty of time on his hands during playoff season. You can follow him on Twitter at @ThatGuyBets.


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