Kansas City Chiefs vs. Buffalo Bills Prediction, Pick: Can Patrick Mahomes and Josh Allen Shine?

One of the most anticipated matchups this NFL season is going down in Week 6. The Buffalo Bills take on the Kansas City Chiefs. John Hyslop shares this YOLO banger for NFL Sunday.

John Hyslop - October 15, 2022, 1:48 PM EDT

5 mins

Kansas City Chiefs vs. Buffalo Bills Prediction, Pick: Can Patrick Mahomes and Josh Allen Shine?

Chiefs vs. Bills Start Time, Where to Watch, and Odds

Date: October 16, 2022
Game Time: 4:25 pm ET
Where to Watch: CBS

Click Here for Chiefs vs Bills Odds

Chiefs vs. Bills Pick

Buffalo Bills/ Kansas City Chiefs Both Teams to Score 30+ (+460) (Bet $100 to win $460)

*Odds available at FanDuel at time of publishing*

Be careful on this one. If you go to BetMGM, they have this exact prop at +350. DraftKings is not much better with +360. Honestly, I'd still bet that but why the hell would you if you could just take +460 at FanDuel? Of course, you're rolling with the +460. It's common sense. If you really want to get wild you could go with both teams to score 35+ (+1480). Why not?

Kansas City Chiefs vs. Buffalo Bills Prediction

I was going to use stats and actual analysis for this but there is no reason to. It's obvious what I think is going to happen and it's also obvious why I think it's going to happen. We're talking about the top offense in the league (yards per play) going against Patrick Mahomes. The Bills will 100% be out for blood in this one. No questions asked. And we just saw the Las Vegas Raiders drop 29 on these Chiefs last week. It would have been 30 if Josh McDaniels knew what he was doing.

That was the second week in a row the Chiefs let someone hang 30 on them. The week before they let Tom Brady and the Tampa Bay Buccaneers put 31 on the board. In fact, every single team the Chiefs have played has put at least 20 on the scoreboard. The thing is, I doubt Kansas City lays down and just takes this offensive onslaught. They have pride and they also have an offense that has gone 30+ in three of five games this season. Don't overthink this one.

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