Liverpool vs Chelsea Lineups, Prediction, Betting Picks & Odds

Liverpool vs Chelsea Game Preview

Liverpool host Chelsea at Anfield on Wednesday in the English League Cup, and the Liverpool vs Chelsea betting odds lean toward the hosts in a cup matchup with real bite.

Liverpool arrive riding a four-game winning streak under Andoni Iraola. Anfield is a hard place to visit when this team has momentum, and right now it has plenty.

Chelsea have struggled for consistency under Xabi Alonso, and a thin attack leaves them short of answers. They are +317 (Polymarket) to win on the road.

History favors the hosts too. Liverpool are undefeated in their last 5 home games against Chelsea in all competitions, and the visitors need a breakthrough to change that story.

Liverpool vs Chelsea Recent Results

Liverpool have scored 11 goals during their current winning run, so the attack is clicking. The depth showed against Tottenham in this competition, a 3-1 win despite wholesale changes to the starting lineup. Alexander Isak leads the line in red-hot form after a productive Premier League start.

Chelsea have been hard to read under Xabi Alonso, with consistency the recurring problem. The ceiling is obvious, though. They beat Leeds United 6-3 in the League Cup, and Danny Welbeck grabbed a brace in that one. Cole Palmer's red card against Tottenham has since left a hole in the attack.

Liverpool vs Chelsea Lineups & Team News

Injuries & Suspensions

Liverpool: Conor Bradley (Injured/out), Jeremie Frimpong (Injured/out), Giovanni Leoni (Injured/out), Dominik Szoboszlai (Injured/out), Hugo Ekitike (Injured/out), Victor Munoz (Injured/doubtful), Florian Wirtz (Injured/doubtful)

Chelsea: Joao Pedro (Injured/out), Emiliano Martinez (Injured/out), Reece James (Injured/out), Jamie Gittens (Injured/out), Emmanuel Emegha (Injured/out), Pep Chavarria (Injured/doubtful), Cole Palmer (Suspended)

Liverpool

Giorgi Mamardashvili is expected to replace Alisson Becker in goal. Florian Wirtz faces a late fitness test after picking up a knock against Brighton on Sunday, and Iraola could opt to rest him regardless. Rio Ngumoha and Trey Nyoni are pushing for starts, which shapes the Liverpool vs Chelsea lineups more than usual.

Chelsea

Alonso is expected to make several changes. Mike Penders is likely to keep his place in goal following Emiliano Martinez's injury, while Romeo Lavia and Estevao Willian are in contention for starting roles. Danny Welbeck could lead the attack.

Liverpool vs Chelsea Predicted Lineup

Liverpool

Formation: 4-2-3-1 (probable)

Predicted Starting Lineup: Probable: G. Mamardashvili; R. Araujo, J. Jacquet, V. v. Dijk, M. Kerkez; A. M. Allister, R. Gravenberch; B. Barcola, T. Nyoni, R. Ngumoha; A. Isak

Chelsea

Formation: 3-4-2-1 (probable)

Predicted Starting Lineup: Probable: M. Penders; L. Colwill, M. Lacroix, W. Fofana; M. Palestra, V. Barco, R. Lavia, J. Hato; Estêvão, M. Rogers; D. Welbeck

Liverpool vs Chelsea Prediction & Best Picks

Our Prediction

Our Liverpool vs Chelsea prediction is a 2-1 Liverpool win. The hosts bring momentum and home advantage, while a depleted Chelsea attack lacks its usual punch. The visitors have enough firepower to score at Anfield, but Liverpool have the edge, and -130 (Polymarket) on the moneyline is a fair price for the better team.

Best Picks

Liverpool to win in the Moneyline market. This is the cleanest of our Liverpool vs Chelsea best picks. The hosts are rolling at Anfield, and Chelsea arrive missing key pieces in attack and in goal.

Both teams to score: Yes in the Both Teams To Score market. Chelsea showed against Leeds that they can find the net, and Liverpool's attack has been relentless. A 2-1 scoreline fits this angle neatly.

Liverpool vs Chelsea Same Game Parlay

Our Liverpool vs Chelsea same game parlay picks stack a Liverpool win, Alexander Isak to score anytime, both teams to score and Wesley Fofana to be shown a card.

Liverpool on the moneyline anchors the parlay. They carry a four-game winning streak into Anfield, and Chelsea's absentees tilt this matchup further toward the hosts.

Alexander Isak in the Anytime Goalscorer market is a natural partner. He has six Premier League goals this season and could retain his place up front.

Yes in the Both Teams To Score market fits the game script. Chelsea scored six against Leeds, and even a weakened attack carries enough threat to find a goal at Anfield.

Wesley Fofana in the To Be Shown A Card market rounds it out. He projects to start in Chelsea's back three and will spend the night dealing with Isak and an in-form Liverpool attack.

Make sure to get the best odds on your Same Game Parlay with Oddschecker's Exclusive Same Game Parlay Comparison Tool.

Same Game Parlay odds correct at time of publishing.

Liverpool vs Chelsea Talking Points

Xabi Alonso's return to Anfield is the storyline. This is his third visit as an opposition manager, but the first time he has led Chelsea against his former club, and he has made it clear past loyalties are set aside, saying he would celebrate if Chelsea scored. Across the touchline sits Andoni Iraola, his childhood friend, which adds a personal edge to a cup night with plenty on the line.

Liverpool vs Chelsea Predictions FAQs

When is the Liverpool vs Chelsea League Cup game?

The game kicks off at 4:00 PM ET / 1:00 PM PT on Wednesday, October 28, 2026.

Where is Liverpool vs Chelsea being played?

The game is being played at Anfield.

Where can I watch Liverpool vs Chelsea?

The game is listed on Sky Sports Main Event, ITV 1 and ITV Interactive.

Who is in the probable lineups for Liverpool vs Chelsea?

Probable Liverpool starters include G. Mamardashvili, V. v. Dijk, A. Isak and B. Barcola. Probable Chelsea starters include M. Penders, M. Lacroix, L. Colwill and D. Welbeck.

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