Read our Real Madrid vs Rayo Vallecano prediction, betting picks, and odds for Saturday's game, plus probable lineups and Same Game Parlay insights.

No. 23 Missouri and Kansas renew the Border Showdown on Friday night with both teams coming off dominant season-opening victories. Missouri won by 11 when the rivalry returned last season, but Kansas now gets the game in Lawrence and has attracted massive larger-wager support as the spread has fallen from a full touchdown toward 5.5. Check out this Missouri vs. Kansas prediction and best bet for Friday, September 11.

Rutgers enters Friday night trying to recover from one of the most stunning losses of the opening college football weekend, and it will do so with AJ Surace replacing injured starter Dylan Lonergan at quarterback. Boston College also struggled badly in its opener, and a market that has cut the Eagles from nearly a touchdown favorite to only three points suggests Rutgers is expected to respond. Check out this Rutgers vs. Boston College prediction and best bet for Friday, September 11.

Frances Tiafoe takes on Ben Shelton in an all-American US Open semifinal on Friday, September 11. Review the latest odds, recent performances and matchup history ahead of their night-session showdown.

Villanova heads into a short-week matchup against No. 24 Louisville after splitting its first two games, while the Cardinals are trying to recover from a draining last-second loss to Ole Miss. Louisville owns the overwhelming talent advantage, but the combination of a quick turnaround, an FCS opponent and likely second-half substitutions creates an interesting totals angle. Check out this Villanova vs. Louisville prediction and best bet for Friday, September 11.

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The Heisman Trophy race enters Week 2 after several contenders delivered explosive opening performances. Can Darian Mensah maintain his early advantage as Arch Manning and Ohio State’s stars prepare for a major showdown? Check out the latest Heisman odds and contender outlooks for this week’s college football action.