Wisconsin and Notre Dame open their seasons under the lights at Lambeau Field in the latest Shamrock Series matchup. The Irish return proven quarterback CJ Carr but must replace an elite running back duo, while Wisconsin is rebuilding an offense that ranked near the bottom of the country despite adding one of the nation's most productive dual-threat transfer quarterbacks. Check out this Wisconsin vs. Notre Dame prediction and best bet for Sunday, September 6.

Louisville and Ole Miss meet in Nashville on Sunday night in a ranked neutral-site matchup featuring two teams coming off nine-plus-win seasons. Ole Miss returns star quarterback Trinidad Chambliss after reaching the CFP semifinals, while Louisville enters with another new quarterback but one of the most consistent programs of the Jeff Brohm era. Check out this Louisville vs. Ole Miss prediction and best bet for Sunday, September 6.

Washington State and Washington renew the Apple Cup on Sunday with the Cougars beginning the Kirby Moore era against a ranked Huskies team that dominated last season's meeting. Washington has the more established quarterback and deeper roster, but a spread of more than three touchdowns creates significant room in a rivalry matchup. Check out this Washington State vs. Washington prediction and best bet for Sunday, September 6.

Daniil Medvedev and Frances Tiafoe meet in the fourth round of the US Open on Sunday, September 6. Both players arrive after impressive straight-sets victories as a place in the quarterfinals awaits in New York.

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