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Roma vs Sassuolo: Lineups, Prediction, Betting Tips & Odds

Roma vs Sassuolo: Lineups, Prediction, Betting Tips & Odds
Luca Price | 16:52 Saturday 7th November 2026

Roma vs Sassuolo predictions, probable lineups, odds and bet builder tips for this Serie A clash at the Stadio Olimpico. Get the betting angle here.

Roma vs Sassuolo Match Summary

Competition

Italian Serie A

Match Date

Saturday 7 November 2026

Match Time

19:45 UK time

Venue (City, Stadium)

Rome, Stadio Olimpico

Roma vs Sassuolo at the Stadio Olimpico pits a side chasing the summit of the 2026/2027 Serie A season against one sliding towards the relegation places.

Third-placed Roma would climb above Inter into second with a win. The Roma vs Sassuolo betting odds make the hosts 4/11 with Bet365, and that feels fair.

Sassuolo arrive 17th and in a proper relegation scrap. They have lost their last four league matches, and the Olimpico is hardly the place to stop the rot.

History is firmly on Roma's side as well. Across the last 24 meetings with Sassuolo in all competitions, they have avoided defeat 22 times.

Roma vs Sassuolo Form

Twelve wins from Roma's last 15 Serie A matches tells you plenty, and the attack is doing the heavy lifting, with Donyell Malen leading the line in sharp form and Matías Soulé supplying the craft. The worry sits at the other end, with at least two goals conceded in each of their last three league outings.

Sassuolo games are rarely dull. Over 2.5 goals has landed in eight of Sassuolo's last 10 Serie A games, mostly because the defence keeps folding. Domenico Berardi and Armand Laurienté are the outlets, both capable of making something out of nothing, and that individual spark is where the visitors' threat comes from.

Roma vs Sassuolo Lineups & Team News

Injuries & Suspensions

Roma: Paulo Dybala (Injured/out), Manu Koné (Injured/out), Lorenzo Pellegrini (Injured/out), Mile Svilar (Injured/out)

Sassuolo: Fedde Leysen (Injured/out), Daniel Boloca (Injured/doubtful), Ismaël Koné (Injured/doubtful)

Roma

The probable Roma vs Sassuolo lineups show Gian Piero Gasperini working around a heavy injury list, with Paulo Dybala, Lorenzo Pellegrini and goalkeeper Mile Svilar all out. Pierluigi Gollini starts in goal behind a back three, while Matías Soulé and Rodrigo Mora support Donyell Malen in a 3-4-2-1.

Sassuolo

Alberto Aquilani is without defender Fedde Leysen, and Daniel Boloca and Ismaël Koné are doubtful. Nemanja Matić anchors the engine room of a 4-3-3, with Domenico Berardi and Armand Laurienté flanking Sebastiano Esposito up front.

Roma vs Sassuolo Predicted Lineup

Roma

Formation: 3-4-2-1 (probable)

Predicted Starting Lineup: Pierluigi Gollini; Mario Hermoso, Leonardo Balerdi, Daniele Ghilardi; Wesley, Niccolò Pisilli, Bryan Cristante, Emanuele Lulli; Matías Soulé, Rodrigo Mora; Donyell Malen (probable)

Sassuolo

Formation: 4-3-3 (probable)

Predicted Starting Lineup: Stefano Turati; Simone Cinquegrano, Duje Ćaleta-Car, Cas Odenthal, Josh Doig; Darryl Bakola, Nemanja Matić, Kristian Thorstvedt; Domenico Berardi, Sebastiano Esposito, Armand Laurienté (probable)

Roma vs Sassuolo Key Stats & Match Facts

  • Roma have scored 2+ goals in 6 out of 9 Serie A matches against Sassuolo.

  • There have been 9+ shots on target in 8 of the last 9 Serie A meetings between Roma and Sassuolo.

  • Sassuolo have received 2+ cards in 6 of their last 7 Serie A matches against Roma.

  • Matías Soulé has recorded 1+ shots on target in 7 of his last 10 Serie A appearances.

  • Domenico Berardi has attempted 3+ shots in 6 of his last 10 Serie A appearances against Roma.

Roma vs Sassuolo Prediction & Best Bets

Our prediction: Roma win, and our Roma vs Sassuolo prediction comes with goals at both ends. The projections give the hosts a 68.76% win probability on the back of an attack in full flow against a Sassuolo defence that keeps shipping goals. They also point to 3.77 goals in total, because Roma's own back line has been leaky enough to let the visitors in.

Best Bets

Over 3.5 in the Total Goals Over/Under market. The model projects a high-scoring game in Rome. Sassuolo have shipped at least two goals in seven of their past eight Serie A fixtures, and that is a defence in genuine trouble. Roma have found the net at least twice in 14 of their previous 15 Serie A matches, so the hosts can carry much of this line on their own.

Yes in the Both Teams To Score market. Roma's attack should score, and Sassuolo's forward line should find a goal against a Roma defence that has leaked. Our projections put both teams scoring at 63.36%, comfortably above the implied probability of the price. With Roma conceding at least twice in each of their last three league outings, Berardi and Laurienté have every reason to fancy their luck.

Roma vs Sassuolo Bet Builder

Our Roma vs Sassuolo bet builder tips lean on the home attack: Donyell Malen shots and shots on target, Roma scoring three or more, and Paulo Dybala anytime.

Donyell Malen over 1.5 shots. He has fired off two or more attempts in each of his last nine Serie A outings, and Roma build their attacks around him.

Malen over 0.5 shots on target. Across his most recent nine Serie A games, he has landed at least one effort on target eight times, and Sassuolo offer little protection.

Roma over 2.5 total home goals. The hosts have put three or more past the opposition in each of the club's last three Serie A fixtures, and this visiting defence is in a bad way.

Paulo Dybala anytime goalscorer. He has scored in four of his previous five Serie A appearances against Sassuolo, but he is listed as injured, so check his status before kick-off.

At the time of writing, this bet builder pays a best price of 21/10 and is as short as 21/10 elsewhere.

Make sure to get the best odds on your Bet Builder with Oddschecker's Exclusive Bet Builder Comparison Tool.

Bet builder odds correct at time of publishing.

Roma vs Sassuolo Talking Points

Alberto Aquilani returns to the Stadio Olimpico to face his former club, and it will not be a gentle homecoming. Over 62,000 Roma supporters are expected. Sassuolo are 15/2 with AK Bets for good reason. The key battle is out wide: Roma are at their best attacking down the wings, which is exactly where Sassuolo struggle to defend, so Wesley pushing on against Domenico Berardi could decide plenty. That flank, open at both ends, is why goals sit at the heart of our Roma vs Sassuolo best bets.

Roma vs Sassuolo Predictions FAQs

When is the Roma vs Sassuolo Italian Serie A game?

Roma vs Sassuolo kicks off on Saturday 7 November 2026 at 19:45 UK time. The match is part of the 2026/2027 Serie A season.

Where is Roma vs Sassuolo being played?

Roma vs Sassuolo is being played at the Stadio Olimpico in Rome.

What competition is Roma vs Sassuolo in?

Roma vs Sassuolo is a Serie A match in the 2026/2027 season.

What formations are expected for Roma vs Sassuolo?

Roma are expected to line up in a probable 3-4-2-1 formation. Sassuolo are expected to line up in a probable 4-3-3 formation.

Disclaimer

Important information: This article may contain links to betting offers or promotions for Roma vs Sassuolo that were available at the time of publication. These offers may have since expired, changed, or no longer be available.

Oddschecker offers are selected from operators that our football experts work with regularly and have first-hand experience of. If you open an account via one of these links, Oddschecker may earn commission. This helps support our coverage and allows us to continue producing expert analysis and football content across Italian Serie A.

Please gamble responsibly. 18+.

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