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Napoli vs Lazio: Lineups, Prediction, Betting Tips & Odds

Napoli vs Lazio: Lineups, Prediction, Betting Tips & Odds
James Smith | 08:37 Sunday 8th November 2026

Napoli vs Lazio predictions, lineups and odds: check probable XIs, Napoli and Lazio form, and bet builder tips ahead of Sunday's Serie A clash in Naples.

Napoli vs Lazio Match Summary

Competition

Italian Serie A

Match Date

Sunday 8 November 2026

Match Time

11:30 UK time

Venue (City, Stadium)

Naples, Diego Armando Maradona

Napoli vs Lazio at the Diego Armando Maradona pits a wounded home side against the Serie A leaders, and the Sunday morning kick-off gives Napoli precious little time to regroup.

Napoli already trail Lazio by 14 points, and losing Alessandro Buongiorno and Stanislav Lobotka to injury makes an awkward job for Massimiliano Allegri even harder.

Lazio arrive top of the table and flying, with nine wins from their last 10 outings against all opponents, and Gustav Isaksen and Tijjani Noslin leading the charge.

Lazio have won their last four away matches against Napoli in all competitions. Another win here would tighten their grip at the summit and leave Napoli's season creaking badly.

Napoli vs Lazio Form

Napoli are a mess right now. They sit mid-table in Serie A and have won just four times in their last 10 games against all opponents. Midweek brought a 4-1 Champions League hammering away at Porto, making it back-to-back defeats, and clean sheets have dried up. Kevin De Bruyne remains their best hope of creating something.

Lazio are the form side in the division. They top the Serie A table, have won their last six league outings and have conceded only eight league goals all campaign. Isaksen and Noslin provide the cutting edge out wide, and this is a side that finishes ruthlessly and attacks down the flanks with real menace.

Napoli vs Lazio Lineups & Team News

Injuries & Suspensions

Napoli: Alisson Santos (Injured/out), Alessandro Buongiorno (Injured/out), Stanislav Lobotka (Injured/out), Costantino Favasuli (Injured/out), Leonardo Spinazzola (Injured/doubtful), David Neres (Injured/doubtful)

Lazio: Mattia Zaccagni (Injured/out), Albert Guðmundsson (Injured/doubtful)

Napoli

The probable Napoli vs Lazio lineups have Allegri going with a 3-5-1-1, with Alex Meret in goal behind a back three of Sam Beukema, Amir Rrahmani and Rafa Marín. Scott McTominay, Billy Gilmour and Frank Anguissa form the engine room, while De Bruyne plays just behind Rasmus Højlund. Spinazzola and Neres are both doubts.

Lazio

Gennaro Gattuso sticks with his 4-3-3, with Christos Mandas in goal. Kenneth Taylor, Davide Frattesi and Reda Belahyane make up the midfield, and Andrea Pinamonti leads the line between Noslin and Isaksen. Zaccagni is out, while forward Albert Guðmundsson is doubtful.

Napoli vs Lazio Predicted Lineup

Napoli

Formation: 3-5-1-1

Predicted Starting Lineup: Alex Meret; Sam Beukema, Amir Rrahmani, Rafa Marín; Noa Lang, Scott McTominay, Billy Gilmour, Frank Anguissa, Matteo Politano; Kevin De Bruyne; Rasmus Højlund

Lazio

Formation: 4-3-3

Predicted Starting Lineup: Christos Mandas; Romano Floriani Mussolini, Oliver Provstgaard, Josip Šutalo, Nuno Tavares; Kenneth Taylor, Reda Belahyane, Davide Frattesi; Gustav Isaksen, Andrea Pinamonti, Tijjani Noslin

Napoli vs Lazio Key Stats & Match Facts

  • Lazio have received 2+ cards in 10 of their last 10 matches vs Napoli (Serie A).

  • Napoli have had 6+ corners in 6 of their last 8 matches vs Lazio (Serie A).

  • There have been 26+ shots taken in 6 of Napoli's last 6 matches (Serie A).

  • Rasmus Højlund has recorded 1+ shots on target in 6 of his last 8 apps (Serie A).

  • Tijjani Noslin has scored or assisted in 5 of his last 7 apps (Serie A).

Napoli vs Lazio Prediction & Best Bets

Our prediction: Napoli are narrow favourites at 11/8 (10Bet), but the projected goals barely split the sides and this is about as balanced as it gets. Lazio, at 85/40 (AK Bets), bring the form, while Napoli bring home advantage and De Bruyne's craft. Our Napoli vs Lazio prediction is goals at both ends in a messy, open game neither side fully controls.

Best Bets

Over 2.5 goals in the Total Goals Over/Under market. Both sides carry a strong attacking threat in a tightly matched contest. This tops our Napoli vs Lazio best bets. There have been over 2.5 goals in Lazio's last five games in Serie A, the projection points to more than three goals here, and a Napoli defence without Buongiorno and Lobotka is not built to keep things quiet.

Both Teams To Score: Yes. Napoli and Lazio are each projected to score around 1.6 goals. The projection rates both teams scoring at 65.57%, and it is easy to see why. Lazio finish ruthlessly, while De Bruyne, Højlund and McTominay give Napoli more than enough to trouble Mandas.

Napoli vs Lazio Bet Builder

Our Napoli vs Lazio bet builder tips lean fully into the league leaders' attack, combining a Lazio goals line, a Lazio win and two Gustav Isaksen legs.

Over 1.5 Total Away Goals: Lazio have scored 2+ goals in 8 of their last 8 Serie A games, and Napoli's leaky back line hardly suggests that run ends here.

Gustav Isaksen Anytime Goalscorer: Isaksen has scored in 4 of his last 5 Serie A appearances, and he will be running at a Napoli side short of defenders.

Lazio to Win: Lazio have won 6 of their last 6 Serie A fixtures. Napoli are favourites on paper, but the visitors are the side in form.

Gustav Isaksen Over 2.5 Player Shots: Isaksen has scored or assisted in 4 of his last 5 Serie A appearances, and that level of involvement should bring plenty of shooting opportunities.

At the time of writing, this bet builder pays a best price of 8/1 and is as short as 13/2 elsewhere.

Make sure to get the best odds on your Bet Builder with Oddschecker's Exclusive Bet Builder Comparison Tool.

Bet builder odds correct at time of publishing.

Napoli vs Lazio Talking Points

The mood in Naples is grim. After the Porto defeat, president Aurelio De Laurentiis cancelled Allegri's pre-match press conference and sent the squad straight into a training retreat. Gattuso, meanwhile, returns to the Maradona to face the club he previously coached, and his side lead the previous meetings with three wins to Napoli's one, while two have finished level. The Napoli vs Lazio betting odds barely separate the two, which feels about right for a fixture with this much needle.

Napoli vs Lazio Predictions FAQs

When is the Napoli vs Lazio Italian Serie A game?

The match is on Sunday 8 November 2026 at 11:30 UK time.

Where is Napoli vs Lazio being played?

Napoli vs Lazio is being played at the Diego Armando Maradona in Naples.

What competition is Napoli vs Lazio in?

Napoli vs Lazio is a Serie A match in the 2026/2027 season.

Disclaimer

Important information: This article may contain links to betting offers or promotions for Napoli vs Lazio that were available at the time of publication. These offers may have since expired, changed, or no longer be available.

Oddschecker offers are selected from operators that our football experts work with regularly and have first-hand experience of. If you open an account via one of these links, Oddschecker may earn commission. This helps support our coverage and allows us to continue producing expert analysis and football content across Italian Serie A.

Please gamble responsibly. 18+.

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