NFL Schedule Release: Opening Lines and Betting Promotions
NFL Week 1 odds are out, and you can get in on the action early with some of the best sports betting promo codes and sign-up offers.
Mark Harris
| 3 Minutes
NFL Schedule Release: Week 1 Odds
The 2025 NFL schedule has been fully released, and football fans everywhere are awaiting their Week 1 matchup that is just over three months out.
So close, yet so far away.
NFL Week 1 is the first chance to see all the teams in action and every team enters with a clean slate, providing a sense of renewal for fans and teams alike. It is one of the biggest sports betting weekends in the United States because it's the first taste of football and allows bettors to see a quick return on their bets, unlike NFL win totals.
Week 1 odds are already public. Some of the game spreads may change due to preseason injuries or other offseason news (where Aaron Rodgers goes, for example), but most of these Week 1 betting lines are going to stay the same.
Here's a look at the NFL Week 1 schedule and odds for each game.
NFL Week 1 odds
Dallas Cowboys at Philadelphia Eagles
Spread: Cowboys +7 (-110), Eagles -7 (-105),
Moneyline: Cowboys +265, Eagles -310
Total: Over/Under 47 points
Game Info: Thursday, Sept. 4 at 8:20 p.m. ET in Philadelphia, PA.
TV: NBC/Peacock
Kansas City Chiefs vs. Los Angeles Chargers
Spread: Chiefs -3 (-110), Chargers +3 (-110)
Moneyline: Chiefs -142, Chargers +130
Total: Over/Under 44.5 points
Game Info: Friday, Sept. 4 at 8 p.m. ET in São Paulo, Brazil.
TV: YouTube
Carolina Panthers at Jacksonville Jaguars
Spread: Panthers +3 (-110), Jaguars -3 (-110)
Moneyline: Panthers +140, Jaguars -144
Total: Over/Under 46.5 points
Game Info: Sunday, Sept. 6 at 1 p.m. ET in Jacksonville, FL.
TV: FOX
Pittsburgh Steelers at New York Jets
Spread: Steelers -3 (-110), Jets +3 (-110)
Moneyline: Steelers -142, Jets +143
Total: Over/Under 39.5 points
Game Info: Sunday, Sept. 6 at 1 p.m. ET in East Rutherford, NJ.
TV: CBS
Las Vegas Raiders at New England Patriots
Spread: Raiders +2.5 (+100), Patriots -2.5 (-110)
Moneyline: Raiders +140, Patriots -140
Total: Over/Under 43.5 points
Game Info: Sunday, Sept. 6 at 1 p.m. ET in Foxborough, MA.
TV: CBS
Arizona Cardinals at New Orleans Saints
Spread: Cardinals -4.5 (-105), Saints +4.5 (-110)
Moneyline: Cardinals -192, Saints +192
Total: Over/Under 41.5 points
Game Info: Sunday, Sept. 6 at 1 p.m. ET in New Orleans, LA.
TV: CBS
Tampa Bay Buccaneers at Atlanta Falcons
Spread: Buccaneers -1.5 (-115), Falcons +1.5 (-105)
Moneyline: Buccaneers -125, Falcons +120
Total: Over/Under 48.5 points
Game Info: Sunday, Sept. 6 at 1 p.m. ET in Atlanta, GA.
TV: FOX
Cincinnati Bengals at Cleveland Browns
Spread: Bengals -5.5 (-110), Browns +5.5 (-105)
Moneyline: Bengals -218, Browns +200
Total: Over/Under 45.5 points
Game Info: Sunday, Sept. 6 at 1 p.m. ET in Cleveland, OH.
TV: FOX
New York Giants at Washington Commanders
Spread: Giants +7 (-110), Commanders -7 (-110)
Moneyline: Giants +280, Commanders -340
Total: Over/Under 45.5 points
Game Info: Sunday, Sept. 6 at 1 p.m. ET in Landover, MD.
TV: FOX
Miami Dolphins at Indianapolis Colts
Spread: Dolphins +1.5 (-110), Colts -1.5 (-102)
Moneyline: Dolphins +100, Colts -115
Total: Over/Under 45.5
Game Info: Sunday, Sept. 6 at 1 p.m. ET in Indianapolis, IN.
TV: CBS
San Francisco 49ers at Seattle Seahawks
Spread: 49ers -1.5 (-115), Seahawks +1.5 (-105)
Moneyline: 49ers -125, Seahawks +105
Total: Over/Under 45.5 points
Game Info: Sunday, Sept. 6 at 4:05 p.m. ET in Seattle, WA.
TV: FOX
Tennessee Titans at Denver Broncos
Spread: Titans +7 (-110), Broncos -7 (-110)
Moneyline: Titans +280, Broncos -350
Total: Over/Under 41.5 points
Game Info: Sunday, Sept. 6 at 4:05 p.m. ET in Denver, CO.
TV: FOX
Detroit Lions at Green Bay Packers
Spread: Lions -1.5 (-105), Packers +1.5 (-115)
Moneyline: Lions -115, Packers -105
Total: Over/Under 49.5 points
Game Info: Sunday, Sept. 6 at 4:25 p.m. ET in Green Bay, WI.
TV: CBS
Houston Texans at Los Angeles Rams
Spread: Texans +2.5 (-105), Rams +2.5 (-115)
Moneyline: Texans +125, Rams -150
Total: Over/Under 46.5 points
Game Info: Sunday, Sept. 6 at 4:25 p.m. ET in Inglewood, CA.
TV: CBS
Baltimore Ravens at Buffalo Bills
Spread: Ravens +1.5 (-110), Bills -1.5 (-110)
Moneyline: Ravens +105, Bills -122
Total: Over/Under 51.5 points
Game Info: Sunday, Sept. 6 at 8:20 p.m. ET in Orchard Park, NY.
TV: NBC
Minnesota Vikings at Chicago Bears
Spread: Vikings +1.5 (-110), Bears -1.5 (-110)
Moneyline: Vikings +102, Bears -105
Total: Over/Under 44.5 points
Game Info: Monday, Sept. 7 at 8:15 p.m. ET in Chicago, IL.
TV: ABC/ESPN
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