Kayla Harrison vs. Amanda Nunes Prediction, Betting Pick, Latest UFC 334 Odds for Saturday, November 14th
Kayla Harrison defends her UFC women's bantamweight championship against returning legend Amanda Nunes in the co-main event of UFC 334 on Saturday, November 14, at Madison Square Garden. Can Nunes reclaim the title she vacated in 2023 and restore her position atop the division, or will Harrison's Olympic-level grappling prove too much for the former two-division champion? Check out this Kayla Harrison vs. Amanda Nunes prediction and best bet for Saturday, November 14.
Peter Alexis - November 14, 2026, 8:15 PM EST
4 Minute ReadKayla Harrison vs. Amanda Nunes Prediction: Can Nunes Take Down Champ Harrison In First Fight in 3 Years?
One of the most anticipated fights in women's MMA history takes place at UFC 334, with bantamweight champion Kayla Harrison defending her title against former two-division champion Amanda Nunes. Harrison enters as a -170 moneyline favorite after capturing the championship in 2025, while Nunes returns from retirement as a +142 underdog seeking to reclaim the belt she previously held.
The matchup brings together two of the most accomplished women in combat sports, with Harrison's elite judo and physical strength facing Nunes' powerful boxing, championship experience and finishing ability. Both fighters have also spent significant time outside the Octagon, creating additional questions about conditioning, timing and their ability to maintain peak performance across five rounds.
Kayla Harrison vs. Amanda Nunes Recent Results
Kayla Harrison
Harrison enters with a 19-1 professional MMA record and has won four consecutive fights since her only career defeat in 2022. The two-time Olympic judo gold medalist captured the UFC bantamweight championship at UFC 316 in June 2025, submitting Julianna Peña with a kimura late in the second round.
However, Harrison has not competed since that championship victory after a neck injury forced her to withdraw from her originally scheduled fight against Nunes in January 2026. The injury required surgery and an extended recovery, making Saturday her first Octagon appearance in more than 17 months.
Amanda Nunes
Nunes returns with a 23-5 record after retiring following her unanimous-decision victory over Irene Aldana at UFC 289 in June 2023. The Brazilian dominated that championship fight over five rounds, defending her bantamweight title before announcing her retirement and vacating both championships.
Her previous victory came against Julianna Peña at UFC 277 in July 2022, when Nunes reclaimed the bantamweight belt with a commanding five-round decision. The former two-division champion has recorded 13 knockout victories and remains one of the most accomplished fighters in UFC history, although she has not competed professionally in more than three years.
Kayla Harrison vs. Amanda Nunes Head to Head
Harrison and Nunes have never faced each other professionally, despite their longstanding connection through the women's MMA scene. The matchup was originally scheduled for January 2026 before Harrison's injury forced its postponement, making Saturday the culmination of a rivalry that has attracted attention for several years.
Kayla Harrison vs. Amanda Nunes Date, Time and Where to Watch
- Date: Saturday, November 14, 2026
- Time: Main card begins at 9 p.m. ET
- Location: Madison Square Garden, New York City
- Streaming: Paramount+
- Scheduled Rounds: 5, UFC Women's Bantamweight Championship
Kayla Harrison vs. Amanda Nunes Odds
- Point Spread: Harrison -9.5 (+100) / Nunes +9.5 (-135)
- Total Rounds: Over 3.5 (-105) / Under 3.5 (-125)
- Moneyline: Harrison -170 / Nunes +142
Click here for complete UFC odds
Kayla Harrison vs. Amanda Nunes Prediction
Harrison's greatest advantage lies in her elite grappling, particularly her ability to close distance, secure powerful takedowns and maintain dominant positions. Her physical strength and judo background have overwhelmed numerous opponents, including Peña, whom she submitted to capture the championship.
However, Nunes represents a different challenge from Harrison's previous UFC opponents. Her striking power, experience against elite competition and ability to create damaging exchanges make her particularly dangerous whenever the fight remains standing.
Nunes has also demonstrated strong takedown defense and defensive grappling throughout her championship career. Although Harrison presents an unusually difficult wrestling and judo challenge, Nunes' experience against accomplished grapplers provides important context for her ability to defend positions and return to her feet.
The most significant uncertainty for Nunes is the lengthy retirement period, with her last professional appearance coming in June 2023. However, Harrison also enters following a substantial absence, and her recovery from neck surgery raises questions about how effectively she can execute repeated takedowns and maintain physical control across five rounds.
The striking exchanges could prove decisive if Nunes prevents Harrison from establishing sustained top position. Nunes has the power to punish entries, attack with combinations and potentially force Harrison to become more cautious about closing distance, creating opportunities to control the pace of the contest.
Kayla Harrison vs. Amanda Nunes Best Bet
- Pick: Amanda Nunes Moneyline (+142) Check out these best odds at FanDuel Sportsbook
Nunes offers an intriguing underdog opportunity because of her superior striking credentials, championship experience and ability to finish fights against elite opponents. If she can consistently defend Harrison's takedowns and force extended standing exchanges, the former champion possesses the offensive tools to reclaim the bantamweight title.
Harrison's grappling remains the most significant concern, particularly if she establishes top control early and limits Nunes' opportunities to attack. However, the combination of Nunes' knockout power, defensive experience and Harrison's long injury-related absence makes +142 an appealing price for the returning former champion.
MMA ODDS & PICKS
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