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Deion Sanders

Colorado vs. Oregon Prediction, Pick, Odds: Stay on the Deion Sanders, Colorado Hype Train

The Colorado Buffaloes have helped the growth of college football, and you should definitely stay on the Deion Sanders and Colorado hype train! This week, the Buffaloes are taking on the Oregon Ducks in Eugene. Jason Radowitz shares his Colorado vs. Oregon prediction and pick.

Jason Radowitz - September 18, 2023, 9:33 AM EDT

5 min

Colorado vs. Oregon Prediction, Pick, Odds: Stay On The Colorado Hype Train!

The Colorado Buffaloes have helped the growth of college football.

The hype around the Buffaloes isn't usual. But it's made for some incredibly entertaining games.

The Buffaloes haven't had a cakewalk through their schedule. They've defeated TCU, Nebraska, and Colorado State. They haven't played some NAIA school. Colorado is 3-0 against legitimate FBS schools with rich histories of success.

But they haven't played a program like Oregon. That's up next.

The Oregon Ducks have defeated Portland State, Texas Tech, and Hawaii. The win against Hawaii last weekend was a blowout, but it took until the final seconds to escape Texas Tech on the road.

Oregon's offense will expose Colorado's defense this week. But can Shedeur Sanders and the Buffaloes' offense continue putting up a lot of points to stick around against Oregon on the road?

Here are our picks, predictions, and odds for Saturday's game between the Colorado Buffaloes vs. Oregon Ducks.

Colorado vs. Oregon Date, Start Time, and Where to Watch

  • Date: September 23, 2023
  • Game Time: 3:30 pm ET
  • Where to Watch: ABC

Colorado vs. Oregon Odds

  • Spread: Colorado +20.5 (-110), Oregon -20.5 (-110)
  • Total Odds: O/U 72.5 (-110)
  • Moneyline Odds: Colorado (+800), Oregon (-1350)

Colorado vs. Oregon Injury Report

Colorado

Questionable: WR Javon Antonio (Shoulder), S Myles Slusher (Undisclosed)

Out: WR/CB Travis Hunter (Undisclosed), TE Louis Passarello (Knee)

Oregon

Questionable: WR Josh Delgado (Undisclosed)

Colorado vs. Oregon Prediction

The Colorado Buffaloes have added 479 yards per game on offense. 418 yards have come in the air, with only 61 on the ground.

Buffalo doesn't have much of a run game. They've relied on Shedeur Sanders at quarterback, who has seen a rise in his Heisman odds throughout the season's first month.

Sanders has thrown ten touchdowns with just one interception. Through three games, he's got 1251 yards. He's a legitimate passer who has NFL potential. He's not just Deion's son.

The pass protection is very good for Colorado. However, the run game is just not very appealing. They've got a good runner in Dylan Edwards, who has earned 25 carries for 136 yards. But they just haven't had significant runs throughout the year.

Meanwhile, on defense, Colorado has allowed 460.3 yards per game. They've given up nearly 200 yards on the ground per game.

The secondary is Colorado's best area on defense. However, Oregon has rushed the football for nearly 230 yards per game. Oregon should have no trouble running the football through Colorado.

The Ducks have averaged nearly 600 yards of offense per game behind Bo Nix. Nix has thrown for 893 yards and eight touchdowns with no interceptions. The run game has been led by Bucky Irving, who has averaged eight yards a carry.

Nix can also rush the football at a high level.

Oregon has done an incredible job keeping Nix clean. The offensive line has looked dominant in pass protection.

Oregon's coverage has been elite on defense, allowing only 158.7 yards per game. Colorado throws the ball a lot. Therefore, Sanders must be firm with the ball and make quality decisions throughout the game.

Oregon is undoubtedly the better team in this game. However, Colorado is still going to be a tough out every weekend.

I'll grab Colorado at +20.5 here.

Note: due to high volume and hype, the odds for this game will move around a lot. I like Colorado from +17 or higher.

Colorado Buffaloes vs. Oregon Ducks Pick

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