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Jason Radowitz is here with an NFL pick for Buffalo Bills vs. Pittsburgh Steelers. Come find out the Bills vs. Steelers prediction, pick, and odds for this Week 5 NFL game.

Bills vs. Steelers Prediction, Pick, Odds: How will Kenny Pickett Perform in First NFL Start for Steelers?

The Pittsburgh Steelers have started 1-3 in life without Big Ben Roethlisberger. Therefore, the Steelers have decided to start their first draft pick, Kenny Pickett, as the quarterback against the Bills this week.

Pickett was the former Pittsburgh Panthers quarterback in college football and got his opportunity to stay in Pittsburgh to play for the Steelers in the NFL.

Sunday will be his first start under center, although he played last week and threw three interceptions in the second half in a loss to the Jets. Mike Tomlin is looking for a spark and will need plenty of sparks on the road against the Buffalo Bills, who are 3-1.

Here are our picks, predictions, and odds for Sunday's game between the Pittsburgh Steelers vs. Buffalo Bills.

Bills vs. Steelers Start Time, Where to Watch, and Odds

  • Date: October 9, 2022
  • Game Time: 1:00 pm ET
  • Where to Watch: CBS

Bills vs. Steelers Odds

Bills vs. Steelers Injury Report


Questionable: S Minkah Fitzpatrick (Knee), DT Cameron Heyward (Elbow) Out: LB T.J. Watt (Pectoral)


Questionable: DT Ed Oliver (Ankle), DT Jordan Phillips (Hamstring), S Jordan Poyer (Undisclosed) Out: CB Tre'Davious White (Knee)

Buffalo Bills vs. Pittsburgh Steelers Prediction

All of the stats on the Steelers' offense can be thrown away. Kenny Pickett is going to start for the Steelers instead of Mitch Trubisky.

While a move was probably necessary sooner rather than later, the Steelers are putting Pickett in a terrible situation in Week 1.

Pittsburgh hasn't even averaged 300 yards of offense per game, and unless we count garbage time, the Steelers likely won't get to 300 yards again on Sunday.

The Bills have allowed just 257 yards per game on the defensive end. Plus, the pass rush has been tremendous and should get to Pickett in this game. If the pass rush comes, the rookie will make some mistakes.

He's playing with a solid offensive line, but it will be challenging to make the right reads and precise throws with one of the best pass-rushing teams coming after you.

On the other hand, the Bills are getting MVP-like work out of Josh Allen. Allen has thrown ten touchdowns and two more rushing touchdowns in four games to start the season. He's also found his favorite target, Stefon Diggs, 31 times for 408 yards and four touchdowns.

Pittsburgh's defense is usually good. But for now, they're without T.J. Watt, and Minkah Fitzpatrick is currently questionable for this game. Pittsburgh's been a bit weaker in coverage this season, but they've done well up front against the run.

The Steelers' defense has allowed 24 points to the Jets and 29 to the Browns in their last two games. Neither of those two teams is a powerhouse offense. However, the Bills are. Buffalo is already averaging over 28 points per game, and they should be able to score over their average in this game against the Steelers.

Pittsburgh has allowed nearly 400 yards on the defensive end. That's usually never a thing with Mike Tomlin as head coach. But the reality is the Steelers are in rebuild mode.

I'll take the Bills -14 in a blowout at home.

Buffalo Bills vs. Pittsburgh Steelers Pick

Article Author


Jason grew up an avid sports fan. His passion for sports writing grew in high school and he developed a blog that was strictly for New York Sports. From his work, you will quickly realize that he loves looking at games from an analytical and numbers perspective and hopes to provide you with that same perspective in his articles.


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