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The Tennessee Titans are finally back in form with a record of 3-2 and now take on an inconsistent Indianapolis Colts team that is 3-2-1. Can Matt Ryan and the Colts shock the Titans this week? Jason Radowitz breaks it down.

Tennessee Titans vs. Indianapolis Colts Prediction, Pick, Odds: Can Matt Ryan and Colts Shock the Titans?

The Tennessee Titans are finally back in form. They've won three straight games and are now 3-2 on the season. Now they'll take on an inconsistent Indianapolis Colts team that is 3-2-1 on the season.

The Colts and Titans are both averaging under three touchdowns per game. Meanwhile, the Titans have allowed over 100 yards more on defense than they've gained on offense.

That's not going to win you many games.

Can the Titans sneak by the Colts and win their fourth straight?

Here are our picks, predictions, and odds for Sunday's game between the Tennessee Titans vs. Indianapolis Colts.

Titans vs. Colts Start Time, Where to Watch, and Odds

  • Date: October 23, 2022
  • Game Time: 1:00 pm ET
  • Where to Watch: CBS

Titans vs. Colts Odds

  • Spread: Titans -3 (-110), Colts +3 (-110)
  • Total Odds: O/U 42.5 (-110)
  • Moneyline Odds: Titans (-145), Saints (+130)

Click Here for Titans vs. Colts Odds

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Titans vs. Colts Injury Report


Questionable: RB Nyheim Hines (Concussion), RB Deon Jackson (Quadricep), RB Jonathan Taylor (Ankle)


Out: WR Treylon Burks (Toe)

Tennessee Titans vs. Indianapolis Colts Prediction

The Tennessee Titans, as mentioned above, have averaged 297 yards of offense while giving up 408.6 yards on defense.

Typically, that's not going to get you wins. But the Titans are 3-2 on the season and could go 4-2 with a win on Sunday.

Ryan Tannehill has led the charge for the Titans with six touchdowns and three interceptions. Through five games, Tannehill hasn't even reached 1000 yards passing. His receiving core is weak, and it shows.

Protection from the offensive line also hasn't been superb either for Tannehill.

Meanwhile, Derrick Henry has rushed 104 times for 408 yards. He's also crossed the goal line five times this year.

The Titans have struggled in coverage on defense and continue to miss tackles. That's led to big plays down the field, which is why the Titans have allowed over 400 yards per game this season.

On the flip side, the Colts have struggled just as badly on the offensive end. They've averaged more yards but fewer points than the Titans.

The Colts earn 377.8 yards per game but just 17.2 points per game. They're not finishing drives around the red zone.

Matt Ryan has thrown eight touchdowns but also seven interceptions in five games. He was supposed to be a significant upgrade for this offense and hasn't played like it. To his defense, the offensive line hasn't performed either.

The run game features former MVP Jonathan Taylor, but he's been injured along with Nyheim Hines. Now Deon Jackson is hurt. All three of those runners are injured and questionable for Sunday's game.

The defense has struggled mainly in the passing game. The Colts have allowed 218.8 yards per game in the air, which doesn't seem all that bad. But the coverage and pass rush hasn't been all that effective this season and could be exploited.

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Meanwhile, the Titans have only averaged 194.2 yards per game in the air. Tennesse isn't a threat in the passing game. The Colts should be able to get some stops defensively and hold on to win this game.

The offense scored 34 against the Jaguars last week. It's headed in the right direction. Back the Colts.

Tennessee Titans vs. Indianapolis Colts Pick

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Article Author


Jason grew up an avid sports fan. His passion for sports writing grew in high school and he developed a blog that was strictly for New York Sports. From his work, you will quickly realize that he loves looking at games from an analytical and numbers perspective and hopes to provide you with that same perspective in his articles.


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