UTEP opens the 2026 season with one of the toughest assignments in college football, traveling to Norman to face No. 10 Oklahoma and one of the nation's most experienced defenses. The Sooners should control the matchup comfortably, but a massive spread and the likelihood of a conservative second half make the full-game total more interesting than the side. Check out this UTEP vs. Oklahoma prediction and best bet for Friday, September 4.

Indiana State makes the short trip to West Lafayette on Friday night for an in-state matchup against a Purdue team entering Year 2 under Barry Odom. The Boilermakers have dominated this series historically, but their reworked offensive line and new skill-position combinations could require some time before the offense reaches full speed. Check out this Indiana State vs. Purdue prediction and best bet for Friday, September 4.

San Jose State hits the road for the second straight week after showing real offensive progress late in a difficult season-opening loss at No. 14 USC. Eastern Michigan enters off a conference win at home, but the Spartans showed enough with new quarterback Luke Weaver to make Friday's short underdog price intriguing. Check out this San Jose State vs. Eastern Michigan prediction and best bet for Friday, September 4.

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Jiri Lehecka and Stefanos Tsitsipas meet Friday in a third-round matchup that looks far more evenly balanced than the rankings suggest. Lehecka owns the recent head-to-head advantage, but Tsitsipas has rediscovered his serve and confidence in New York, making the total more attractive than trying to choose a winner.

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The Los Angeles Rams have shortened from +550 to +500 to win Super Bowl LXI after Aaron Donald officially ended his two-year retirement and rejoined the franchise. The move itself was relatively small because Donald had been ramping up throughout August and a return was increasingly expected, but Los Angeles now enters the season with arguably the NFL's most loaded roster and a troubling historical trend attached to its price.

Pete Crow-Armstrong has taken complete control of the NL MVP race after an incredible five-home-run weekend against Cincinnati. PCA has surged from roughly -150 just days ago to -1600, while Shohei Ohtani has fallen from +120 to +900 as the Cubs star continues building one of baseball's best all-around seasons.