Best Bets 

Stefanos Tsitsipas is another of the younger generation who has enjoyed a breakout year in 2018 so far, with some great results on the European clay courts. 

Though his game is obviously suited to the clay, he's not quite so one-dimensional as others with a similar style and if he can improve his court positioning and movement he can beome one of the best all court players on the tour. 

John Isner does not have a good record at Wimbledon, with this being the first time he's advanced to the fourth round in ten appearances at the All England club. 

His relative success this year has been about obviously serving great and then building pressure on his opponent's serve to create opportunities. That won't be so easy against the Greek youngster, who has a good serve that will only improve over time and will should hold most of his service games comfortably in this match. 

Isner won a tight 7-6 7-6 encounter against Tsitsipas in Shanghai last season and with the Greek visibly improving in that short time I think he will come out on top in this one on the grass at SW19.

Stefanos Tsitsipas - 1pt @ 8/5

Mackensie McDonald has had a dream run at Wimbledon this year, having never previously been passed the second round at any Grand Slam. 

Raonic has been on his way back from injury has ahd his injury problems over the last year and altough he is very much at home on the grass and at Wimbledon, I don't envisionage him being at his best today having pulled out of the second round at Queen's only a couple of weeks ago. 

It's a given that both men will hold their serve the majority of the time, with long rallies at a premium and if the American can force a tie break in two or three sets, I think he has a good chance of winning at least one.

Mackensie McDonald To Win A Set - 1pt @ 11/10