March Madness Odds & Schedule Today: Sunday's Best Bets & Expert Picks for NCAA Tournament

Get ready for the fourth day of the 2025 NCAA Tournament with the latest odds for every matchup. Below, you'll find the point spreads, moneylines, and totals for each Sunday Round of 32 game, helping you make informed picks as March Madness wraps up the opening weekend.

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2025 March Madness Odds

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2025 March Madness Second Round Odds: Round of 32

UConn vs. Florida Odds (Sunday, March 23; 12:10 PM ET)

• Spread: UConn +9.5 (-110), Florida -9.5 (-110)​
• Moneyline: UConn +410, Florida -500
• Total: Over 145.5 (-110), Under 145.5 (-110)

The Florida Gators will look to take out the feisty defending champions today when they take on the UConn Huskies in the NCAA Tournament Round of 32. Can Walter Clayton Jr. and the Gators win by double digits in this March Madness Second Round showdown? Jason Radowitz thinks so, and backs up the Gators in his UConn vs. Florida prediction for Sunday's Round of 32 clash.

Click here for UConn vs. Florida Prediction and Betting Pick

Baylor vs. Duke Odds (Sunday, March 23; 2:40 PM ET)

• Spread: Baylor +12.5 (-110), Duke -12.5 (-105)
• Moneyline: Baylor +650, Duke -800
• Total: Over 145.5 (-109), Under 145.5 (-108)

The Duke Blue Devils will take on the Baylor Bears on Sunday afternoon, and Cooper Flagg will look to extend his team's NCAA Tournament after returning from injury. Can the Blue Devils make quick work of the Bears on Sunday afternoon in the Round of 32? Matt MacKay is feeling confident in the 1-seed here to control the game flow in his Baylor vs. Duke prediction for the March Madness Second Round.

Click here for Baylor vs. Duke Best Bet

Illinois vs. Kentucky Odds (Sunday, March 23; 5:15 PM ET)

• Spread: Illinois -1.5 (-110), Kentucky +1.5 (-110)
• Moneyline: Illinois -130, Kentucky +115
• Total: Over 149.5 (-110), Under 149.5 (-108)

The Illinois Fighting Illini and Kentucky Wildcats are set to deliver one of the best games of Sunday's Round of 32. Can Kasparus Jakucionis and the Illini take out the 3-seed Wildcats in Mark Pope's first season as head coach? The pressure is on the Wildcats, explains Jason Radowitz in his Illinois vs. Kentucky prediction and best bet for the Round of 32.

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Saint Mary's vs. Alabama Odds (Sunday, March 23; 6:10 PM ET)

• Spread: Saint Mary's +5.5 (-110), Alabama -5.5 (-110)
• Moneyline: Saint Mary's +210, Alabama -230
• Total: Over 149.5 (-110), Under 149.5 (-108)

The Alabama Crimson Tide will put their high-octane offense to the test against the sharp Saint Mary's defense on Sunday evening. Can Mark Sears and the Tide break through the press, or will they struggle to find the bottom of the basket early? Christian Odjakjian is expecting a bit of a slow start in his Saint Mary's vs. Alabama betting pick for the NCAA Tournament Round of 32.

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Colorado State vs. Maryland Odds (Sunday, March 23; 7:10 PM ET)

• Spread: Colorado State +7.5 (-110), Maryland -7.5 (-105)
• Moneyline: Colorado State +290, Maryland -350
• Total: Over 144.5 (-105), Under 144.5 (-110)

The Maryland Terrapins will look to punch their ticket to Sweet 16 by overwhelming the 12-seeded Colorado State Rams on Sunday night. Can Derik Queen and the Terps take care of business against Nique Clifford and the Rams and set up their date with the Florida Gators? Next Level Bets is feeling confident about the Terps and explains why in his Colorado State vs. Maryland Pick for the NCAA Tournament Round of 32.

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Ole Miss vs. Iowa State Odds (Sunday, March 23; 7:45 PM ET)

• Spread: Ole Miss +5.5 (-110), Iowa State -5.5 (-109)
• Moneyline: Ole Miss +190, Iowa State -210
• Total: Over 145.5 (-110), Under 145.5 (-105)

The Iowa State Cyclones will try to avoid the upset against the Ole Miss Rebels without their best player, Keshon Gilbert. Will they struggle offensively in the absence of their star in the Round of 32? Matt MacKay breaks down this Ole Miss vs. Iowa State prediction and adds his best betting pick for the March Madness Second Round on Sunday night.

Click here for Ole Miss vs. Iowa State Analysis

New Mexico vs. Michigan State Odds (Sunday, March 23; 8:40 PM ET)

• Spread: New Mexico +7.5 (-108), Michigan State -7.5 (-110)
• Moneyline: New Mexico +275, Michigan State -320
• Total: Over 148.5 (-105), Under 148.5 (-110)

The New Mexico Lobos will look for a second-straight upset with a take down of the Michigan State Spartans on Sunday night. Can Donovan Dent and the Lobos advance past Tom Izzo's Spartans tonight? Next Level Bets is giving them a reasonable chance to at least cover the spread in this New Mexico vs. Michigan State prediction for the March Madness Round of 32.

Click here for New Mexico vs. Michigan State Prediction

Oregon vs. Arizona Odds (Sunday, March 23; 9:40 PM ET)

• Spread: Oregon +3.5 (-107), Arizona -3.5 (-110)
• Moneyline: Oregon +150, Arizona -170
• Total: Over 152.5 (-110), Under 152.5 (-110)

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COLLEGE BASKETBALL ODDS & PICKS

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