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Arkansas vs. LSU Prediction, Betting Pick, Latest College World Series Semifinal Odds

The Arkansas Razorbacks will take on the LSU Tigers on Wednesday, June 18th in the second semifinal matchup of the College World Series. Can Arkansas get revenge for Saturday's original defeat, or will the Tigers cruise back to their second-straight College World Series Final with a win? Matt MacKay analyzes this Arkansas vs. LSU showdown in the College World Series semifinals.

Matt MacKay - June 18, 2025, 12:40 PM EDT

5 Minute Read

Arkansas vs. LSU Prediction, Betting Pick, Latest College World Series Odds

The 2025 Men's College World Series is down to the final four teams ahead of today's two Semifinal matchups in Omaha, Nebraska. The prime-time game features No. 3 Arkansas vs. No. 6 LSU in an SEC showdown.

The Razorbacks need to win two consecutive games against the Tigers to advance to the National Championship series against either Coastal Carolina or Louisville. LSU can advance with a win on Wednesday night over one of their top divisional rivals.

Handicapper Matt MacKay is here with a prediction and betting pick on tonight's College World Series Semifinal game between the Arkansas Razorbacks and the LSU Tigers. Follow Matt's X account for more betting insight and free picks.

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Arkansas vs. LSU Odds

  • Moneyline: Arkansas (-120), LSU (+100)
  • Spread: Arkansas -1.5 (+135), LSU +1.5 (-160)
  • Total: Over 11 (-115), Under 11 (-115)

Arkansas vs. LSU Date, Time, and Where to Watch

  • Date: Wednesday, June 18th, 2025
  • Game Time: 7:00 PM ET
  • Where to Watch: ESPN, ESPN+

Click here for the latest Arkansas vs. LSU Odds

Arkansas vs. LSU Prediction

Arkansas won't have their best pitchers available against LSU for Game 1 of this Semifinal matchup. The Razorbacks have leaned on their defense to get to this point. They shut down Murray State in a dominant 3-0 win on Monday in an Elimination Game thanks to pitcher Gage Wood's no-hitter, recording 19 strikeouts.

The Razorbacks followed up their 3-0 shutout win against Murray State with a 7-3 win over No. 15 UCLA on Tuesday. Tonight, they'll face a familiar opponent in LSU for the fifth time this season. The Tigers are 3-1 SU against Arkansas. Their most recent head-to-head matchup against the Razorbacks resulted in a 4-1 win on Saturday in a Double Elimination Round.

LSU's offense is firing on all cylinders. The Tigers just scored nine runs to beat No. 15 UCLA during Tuesday's 9-5 win in a Double Elimination Round game. Now, LSU is one win away from going back to the College World Series Championship Final for the second time since winning it in 2023.

Oddsmakers are leaning toward Arkansas in a must-win spot, laying -120 odds on the Razorbacks' moneyline. LSU is even money (+100 odds), making them a slight underdog, despite going 3-1 SU against Arkansas this season. The run total is set high at 11.5, with -115 odds on either side of this line. The Tigers are -160 odds to cover their +1.5 run line as underdogs.

The Razorbacks have never won a National Championship in school history. They undoubtedly have more motivation. However, there is also the added pressure of having to beat a talented division rival twice in a row to get to the Championship Final on Saturday.

Wood and other Arkansas pitcher, Zach Root, won't be available. Neither will Gabe Gaeckle or Aiden Jimenez, forcing the Razorbacks to dip into their depth chart on the mound. This gives LSU an edge in tonight's first Semifinal game.

Without Arkansas having their top pitching talent available tonight, it feels like there's a lot of value on LSU to win outright as the underdog. They have minimal pressure compared to the Razorbacks, while their offense has been more consistent.

Let's bet one unit on LSU's moneyline at +100 odds. The Tigers should have enough in their lineup and on the mound to eliminate Arkansas in tonight's Semifinal matchup and advance to the 2025 Mens' College World Series Championship Final on Saturday.

Arkansas vs. LSU Pick

  • Pick: LSU Moneyline (+100) Click here to see which sportsbook has the best Arkansas vs. LSU odds

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